Active substances
Acetylsalicylic acid + Butalbital + Caffeine
- US FDA 16
- Health Canada 5
- US price lines 1
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| LANORINAL | 325MG;50MG;40MG | capsule · oral | SANDOZ | Prescription | 28 Dec 1981 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | capsule · oral | MPP PHARMA | Prescription | 13 Jun 2007 |
| FIORINAL | 325MG;50MG;40MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | ALLERGAN | Discontinued | 4 May 1976 |
| FIORINAL | 325MG;50MG;40MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | capsule · oral | ALLERGAN | Discontinued | 4 May 1976 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | WATSON LABS | Discontinued | 21 Feb 1979 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | HIKMA INTL PHARMS | Discontinued | 5 Jun 1979 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | ACTAVIS ELIZABETH | Discontinued | 25 Jul 1979 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | PURACAP PHARM | Discontinued | 30 Apr 1980 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | FOSUN PHARMA | Discontinued | 30 Jul 1980 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | capsule · oral | WATSON LABS | Discontinued | 16 Jun 1982 |
| LANORINAL | 325MG;50MG;40MG | tablet · oral | LANNETT | Discontinued | 1 Jul 1982 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | STRIDES PHARMA | Discontinued | 22 Sep 2016 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 500MG;50MG;40MG | capsule · oral | LGM PHARMA | Discontinued | 18 Oct 2021 |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | IVAX PHARMS | Discontinued | |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | QUANTUM PHARMICS | Discontinued | |
| BUTALBITAL, ASPIRIN AND CAFFEINE | 325MG;50MG;40MG | tablet · oral | HALSEY | Discontinued |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| APO-BUTALBITAL-ACETYLSALICYLIC ACID-CAFFEINE | 02554690 | 40 MG; 50 MG; 330 MG | CAPSULE · ORAL | APOTEX INC |
| FIORINAL | 00226327 | 50 MG; 330 MG; 40 MG | CAPSULE · ORAL | ARALEZ PHARMACEUTICALS CANADA INC |
| TEVA-TECNAL | 00608211 | 40 MG; 330 MG; 50 MG | TABLET · ORAL | TEVA CANADA LIMITED |
| TEVA-TECNAL | 00608238 | 50 MG; 40 MG; 330 MG | CAPSULE · ORAL | TEVA CANADA LIMITED |
| TRIANAL TABLET | 01971409 | 40 MG; 50 MG; 330 MG | TABLET · ORAL | LABORATOIRE RIVA INC. |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE | $0.94823 | per EA | 23 Sep 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Components
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.