Active substances
Acetylsalicylic acid + Caffeine + Paracetamol
- US FDA 4
- UK MHRA 13
- US price lines 1
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| EXCEDRIN (MIGRAINE RELIEF) | 250MG;250MG;65MG | tablet · oral | HALEON US HOLDINGS | Over-the-counter | 14 Jan 1998 |
| ACETAMINOPHEN, ASPIRIN AND CAFFEINE | 250MG;250MG;65MG | tablet · oral | PERRIGO | Over-the-counter | 26 Nov 2001 |
| ACETAMINOPHEN, ASPIRIN AND CAFFEINE | 250MG;250MG;65MG | tablet · oral | GRANULES | Over-the-counter | 23 Feb 2021 |
| ACETAMINOPHEN, ASPIRIN AND CAFFEINE | 250MG;250MG;65MG | tablet · oral | AUROBINDO PHARMA LTD | Over-the-counter | 2 Feb 2022 |
UK MHRA United Kingdom — marketing authorisations
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | ASPIRIN-ACETAMINOPHEN-CAFFEINE TABLET | $0.06482 | per EA | 23 Sep 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Components
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), MHRA category lists of UK marketing authorisations (Open Government Licence v3.0), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.