Active substance
Amantadine
- SFDA 1
- US FDA 43
- Health Canada 3
- US price lines 3
- NHS prices 2
- Safety 2
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| PK-MERZ | 100 mg | Tablet · Oral use | 100 Tablet Container | SAR 66.20 | NCE · Prescription | MERZ PHARMACEUTICAL | Valid |
Indications — CHI Daman Drug Formulary
MULTIPLE SCLEROSIS; PARKINSONISM; SCHIZOPHRENIA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | UPSHER SMITH LABS | Prescription | 7 Jan 1987 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | SANDOZ | Prescription | 18 Feb 1987 |
| AMANTADINE HYDROCHLORIDE | 50MG/5ML | syrup · oral | CHARTWELL RX | Prescription | 28 Jun 1993 |
| AMANTADINE HYDROCHLORIDE | 50MG/5ML | syrup · oral | AUROBINDO PHARMA USA | Prescription | 28 Oct 1994 |
| AMANTADINE HYDROCHLORIDE | 50MG/5ML | syrup · oral | PHARM ASSOC | Prescription | 17 Jul 1995 |
| AMANTADINE HYDROCHLORIDE | 50MG/5ML | syrup · oral | PHARMOBEDIENT | Prescription | 24 Dec 1998 |
| AMANTADINE HYDROCHLORIDE | 100MG | tablet · oral | UPSHER SMITH LABS | Prescription | 16 Dec 2002 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | BIONPHARMA | Prescription | 29 May 2008 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | ZYDUS PHARMS | Prescription | 31 May 2016 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | STRIDES PHARMA | Prescription | 7 Jun 2017 |
| AMANTADINE HYDROCHLORIDE | 100MG | tablet · oral | STRIDES PHARMA | Prescription | 9 Jun 2017 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | HERITAGE PHARMA | Prescription | 12 Jun 2017 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | ALEMBIC | Prescription | 21 Jun 2017 |
| GOCOVRI | EQ 68.5MG BASE; EQ 137MG BASE | capsule, extended release · oral | SUPERNUS PHARMS | Prescription | 24 Aug 2017 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | RISING | Prescription | 2 Mar 2020 |
| AMANTADINE HYDROCHLORIDE | 100MG | tablet · oral | PHARMOBEDIENT | Prescription | 10 Mar 2020 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | RUBICON RESEARCH | Prescription | 21 May 2020 |
| AMANTADINE HYDROCHLORIDE | 100MG | tablet · oral | ALEMBIC | Prescription | 15 Oct 2020 |
| AMANTADINE HYDROCHLORIDE | 50MG/5ML | syrup · oral | PHARMOBEDIENT | Prescription | 20 Aug 2021 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | ONESOURCE | Prescription | 18 Feb 2022 |
| AMANTADINE HYDROCHLORIDE | 100MG | capsule · oral | HUMANWELL PURACAP | Prescription | 20 Dec 2022 |
| AMANTADINE HYDROCHLORIDE | 100MG | tablet · oral | ZHEJIANG JUTAI PHARM | Prescription | 26 Sep 2024 |
| SYMMETREL | 50MG/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | syrup · oral | ENDO PHARMS | Discontinued | 14 Feb 1968 |
| SYMMETREL | 50MG/5ML | syrup · oral | ENDO PHARMS | Discontinued | 20 Jul 1976 |
| SYMMETREL | 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | ENDO PHARMS | Discontinued | 3 Nov 1980 |
18 more — full table
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| ODAN-AMANTADINE SYRUP | 02538601 | 10 MG / ML | SYRUP · ORAL | ODAN LABORATORIESLTD |
| PDP-AMANTADINE HYDROCHLORIDE CAPSULES | 01990403 | 100 MG | CAPSULE · ORAL | PENDOPHARM DIVISION OF PHARMASCIENCE INC |
| PDP-AMANTADINE HYDROCHLORIDE SYRUP | 02022826 | 50 MG / 5 ML | SYRUP · ORAL | PENDOPHARM DIVISION OF PHARMASCIENCE INC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | AMANTADINE 100 MG CAPSULE | $0.14251 | per EA | 23 Sep 2026 |
| US NADAC | AMANTADINE 100 MG TABLET | $0.31434 | per EA | 23 Sep 2026 |
| US NADAC | AMANTADINE 50 MG/5 ML SOLUTION | $0.04977 | per ML | 23 Sep 2026 |
| NHS Drug Tariff | Amantadine 100mg capsules | £7.55 | 56 capsule | 1 Oct 2026 |
| NHS Drug Tariff | Amantadine 50mg/5ml oral solution sugar free | £140.00 | 150 ml | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Safety signals and safety-related labeling changes
- US FDA 10 Jul 2025 GOCOVRI — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Adverse Reactions; Patient Counseling Information / Patient Information / Medication Guide - US FDA 10 Jul 2025 OSMOLEX ER — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Adverse Reactions; Patient Counseling Information / Patient Information / Medication Guide
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.