Active substances
Atropine + Diphenoxylate
- SFDA 3
- US FDA 39
- Health Canada 1
- US price lines 2
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| DIAXINE TABS | 2.5, 0.025 mg | Tablet · Oral use | 30 Blister | SAR 2.00 | Generic · Prescription | Hikma Pharmaceuticals PLC | Withdrawn by MAH · Not Marketed |
| INTARD TABS. 2.5MG | 2.5, 0.025 mg | Tablet · Oral use | 20 Blister | SAR 6.25 | Generic · Prescription | Gulf Pharmaceutical Industries (Julphar) | Withdrawn by MAH · Not Marketed |
| LOMOTIL | 2.5, 0.025 mg | Tablet · Oral use | 20 Blister | SAR 10.35 | NCE · Prescription | G.D.SEARLE | Withdrawn by MAH · Not Marketed |
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| LOMOTIL | 0.025MG;2.5MG | tablet · oral | PFIZER | Prescription | 15 Sep 1960 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | LANNETT | Prescription | 21 Feb 1978 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | ANI PHARMS | Prescription | 29 Oct 1979 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG/5ML;2.5MG/5ML | solution · oral | HIKMA PHARMS | Prescription | 3 May 1982 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | UNICHEM | Prescription | 13 Nov 2018 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | LEADING | Prescription | 20 Feb 2020 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | SPECGX LLC | Prescription | 6 Oct 2020 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | CHARTWELL RX | Prescription | 21 Oct 2020 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | WINDER LABS LLC | Prescription | 27 Jan 2021 |
| LOMOTIL | 0.025MG/5ML;2.5MG/5ML | solution · oral | GD SEARLE LLC | Discontinued | 19 Oct 1961 |
| DI-ATRO | 0.025MG;2.5MG | tablet · oral | MD PHARM | Discontinued | 18 Apr 1977 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | SUN PHARM INDUSTRIES | Discontinued | 3 Jun 1977 |
| LONOX | 0.025MG;2.5MG | tablet · oral | FOSUN PHARMA | Discontinued | 7 Jun 1977 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | R AND S PHARMA | Discontinued | 5 Jul 1977 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | QUAGEN | Discontinued | 17 Nov 1977 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | KV PHARM | Discontinued | 27 Jan 1978 |
| COLONAID | 0.025MG/5ML;2.5MG/5ML | solution · oral | MEDPOINTE PHARM HLC | Discontinued | 13 Feb 1978 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | INWOOD LABS | Discontinued | 9 Mar 1978 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | WATSON LABS | Discontinued | 22 Jun 1978 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | PVT FORM | Discontinued | 22 Dec 1978 |
| DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE | 0.025MG;2.5MG | capsule · oral | SCHERER RP | Discontinued | 6 Apr 1981 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | PARKE DAVIS | Discontinued | 17 Jul 1981 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | FOSUN PHARMA | Discontinued | 28 Aug 1981 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | HIKMA | Discontinued | 15 Mar 1982 |
| DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE | 0.025MG;2.5MG | tablet · oral | USL PHARMA | Discontinued | 29 Mar 1982 |
14 more — full table
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| LOMOTIL | 00036323 | 2.5 MG; .025 MG | TABLET · ORAL | PFIZER CANADA ULC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET | $0.13885 | per EA | 23 Sep 2026 |
| US NADAC | LOMOTIL 2.5-0.025 MG TABLET | $2.99096 | per EA | 23 Sep 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Components
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.