Regulatory PathRegulatory requirements compared

Active substances

Benserazide + Levodopa

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade nameStrengthForm · routePackPublic priceTypeCompanyStatus
MADOPAR 250 MG TABS200,50 mg,mgTablet · Oral use30 BlisterSAR 62.80NCE · PrescriptionROCHEValid
MADOPAR 125MG HBS CAPS100,25 mgCapsule, hard · Oral use100 BlisterSAR 87.05NCE · PrescriptionROCHEWithdrawn by MAH · Not Marketed
MADOPAR 125MG HBS CAPS100,25 mgCapsule, hard · Oral use30 BlisterSAR 29.35NCE · PrescriptionROCHEWithdrawn by MAH · Not Marketed
MADOPAR 250 MG CAPS200,50 mg,mgTablet · Oral use100 BlisterSAR 186.00NCE · PrescriptionROCHEWithdrawn by MAH · Not Marketed
MADOPAR 250 MG TABS200,50 mgTablet · Oral use100 BlisterSAR 186.00NCE · PrescriptionROCHEWithdrawn by MAH · Not Marketed
Indications — CHI Daman Drug Formulary

HYPERTENSION; PARKINSONISM

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
PROLOPA CAP 100-2500386464100 MG; 25 MGCAPSULE · ORALHOFFMANN-LA ROCHE LIMITED
PROLOPA CAP 200-5000386472200 MG; 50 MGCAPSULE · ORALHOFFMANN-LA ROCHE LIMITED
PROLOPA CAP 50-12.50052259712.5 MG; 50 MGCAPSULE · ORALHOFFMANN-LA ROCHE LIMITED

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
NHS Drug TariffCo-beneldopa 12.5mg/50mg capsules£13.09100 capsule1 Oct 2026
NHS Drug TariffCo-beneldopa 12.5mg/50mg dispersible tablets sugar free£5.90100 tablet1 Oct 2026
NHS Drug TariffCo-beneldopa 25mg/100mg capsules£6.91100 capsule1 Oct 2026
NHS Drug TariffCo-beneldopa 25mg/100mg dispersible tablets sugar free£10.45100 tablet1 Oct 2026
NHS Drug TariffCo-beneldopa 25mg/100mg modified-release capsules£12.77100 capsule1 Oct 2026
NHS Drug TariffCo-beneldopa 50mg/200mg capsules£11.78100 capsule1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

  • 5.1.3. Medicines for parkinsonism · core
    Therapeutic equivalent to levodopa + carbidopa for Parkinson disease

Components

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.