Active substance
Bisoprolol
- SFDA 33
- US FDA 14
- Health Canada 24
- US price lines 3
- NHS prices 6
- WHO EML 4
- Safety 2
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| BISCOR 10MG F.C. TABLETS | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 31.60 | Generic · Prescription | Med City Pharma | Valid |
| BISCOR 5MG F.C. TABLETS | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 22.30 | Generic · Prescription | Med City Pharma | Valid |
| BISOLOL 10 mg Tablet | 10 mg | Tablet · Oral use | 30 Blister | SAR 23.05 | Generic · Prescription | AJA PHARMACEUTICAL INDUSTRIES | Valid |
| BISOLOL 2.5 mg Tablet | 2.5 mg | Tablet · Oral use | 30 Blister | SAR 10.80 | Generic · Prescription | AJA PHARMACEUTICAL INDUSTRIES | Valid |
| BISOLOL 5 mg Tablet | 5 mg | Tablet · Oral use | 30 Blister | SAR 16.25 | Generic · Prescription | AJA PHARMACEUTICAL INDUSTRIES | Valid |
| Beta Cor 5mg Tablet | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 11.90 | Generic · Prescription | Jordan Sweden Medical and Sterilization Co. | Valid |
| Bistonal | 10 mg | Film-coated tablet · Oral use | 28 Blister | SAR 21.50 | Generic · Prescription | ALTAIF PHARMACEUTICALS COMPANY | Valid |
| Bistonal | 5 mg | Film-coated tablet · Oral use | 28 Blister | SAR 15.15 | Generic · Prescription | ALTAIF PHARMACEUTICALS COMPANY | Valid |
| Bistonal | 2.5 mg | Film-coated tablet · Oral use | 28 Blister | SAR 10.10 | Generic · Prescription | ALTAIF PHARMACEUTICALS COMPANY | Valid |
| CARDEX | 2.5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 13.35 | Generic · Prescription | ACINO PHARMA AG | Valid |
| CARDEX 10 MG FILM COATED TABLET | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 28.45 | Generic · Prescription | ACINO PHARMA AG | Valid |
| CARDEX 5 MG FILM COATED TABLET | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 20.05 | Generic · Prescription | ACINO PHARMA AG | Valid |
| CARDICOR 10MG FILM COATED TABLET | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 30.10 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| CARDICOR 2.5MG FILM COATED TABLET | 2.5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 16.60 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| CARDICOR 5MG FILM COATED TABLET | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 24.85 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| CARDIOPROL 10MG TABLETS | 10 mg | Tablet · Oral use | 30 Blister | SAR 23.05 | Generic · Prescription | The Jordanian Pharmaceutical Manufacturing Medical Equipment Co. Ltd. (JPM) | Valid |
| CARDIOPROL 5MG TABLETS | 5 mg | Tablet · Oral use | 30 Blister | SAR 16.25 | Generic · Prescription | The Jordanian Pharmaceutical Manufacturing Medical Equipment Co. Ltd. (JPM) | Valid |
| CONCOR | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 29.25 | NCE · Prescription | Merck Healthcare KGaA | Valid |
| CONCOR | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 35.40 | NCE · Prescription | Merck Healthcare KGaA | Valid |
| CONCOR COR | 2.5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 19.55 | NCE · Prescription | Merck Healthcare KGaA | Valid |
| Cardioprol | 10 mg | Film-coated tablet · Oral use | 1000 Blister | SAR 666.50 | Generic · Prescription | The Jordanian Pharmaceutical Manufacturing Medical Equipment Co. Ltd. (JPM) | Valid |
| Cardioprol | 5 mg | Film-coated tablet · Oral use | 1000 Blister | SAR 488.30 | Generic · Prescription | The Jordanian Pharmaceutical Manufacturing Medical Equipment Co. Ltd. (JPM) | Valid |
| OBSOL 10 MG FILM COATED TABLET | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 23.05 | Generic · Prescription | MS Pharma Saudi (MSPS) | Valid |
| OBSOL 5 MG FILM COATED TABLET | 5 mg | Film-coated tablet · Oral use | 30 Blister | SAR 16.25 | Generic · Prescription | MS Pharma Saudi (MSPS) | Valid |
| SELECTA 10MG F.C. TABLETS | 10 mg | Film-coated tablet · Oral use | 30 Blister | SAR 33.60 | Generic · Prescription | Jamjoom Pharmaceuticals Factory Company | Valid |
8 more — full table
Indications — CHI Daman Drug Formulary
ARRHYTHMIA; ATRIAL FIBRILLATION; CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE/ HEADACHE; NON-ST WAVE ELEVATED MYOCARDIAL INFARCTION (NSTEMI); ST-WAVE ELEVATED MYOCARDIAL INFARCTION (STEMI); VENTRICULAR TACHYCARDIA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| BISOPROLOL FUMARATE | 5MG; 10MG; 2.5MG | tablet · oral | RUBICON RESEARCH | Prescription | 16 Nov 2000 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | TP ANDA HOLDINGS | Prescription | 25 Oct 2002 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | AUROBINDO PHARMA | Prescription | 27 Dec 2006 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | UNICHEM | Prescription | 18 Aug 2009 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | ALEMBIC | Prescription | 11 Jan 2017 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | NOVITIUM PHARMA | Prescription | 29 Oct 2021 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | ZYDUS LIFESCIENCES | Prescription | 25 Jul 2022 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | PRINSTON INC | Prescription | 14 Jul 2023 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | HARMAN FINOCHEM | Prescription | 18 Jan 2024 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | UNIQUE PHARM | Prescription | 16 Apr 2025 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | MICRO LABS | Prescription | 9 Mar 2026 |
| ZEBETA | 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | TEVA BRANDED PHARM | Discontinued | 31 Jul 1992 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | TEVA PHARMS | Discontinued | 26 Jun 2001 |
| BISOPROLOL FUMARATE | 5MG; 10MG | tablet · oral | NATCO PHARMA USA | Discontinued | 14 Dec 2005 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| AG-BISOPROLOL | 02521156 | 5 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| AG-BISOPROLOL | 02521164 | 10 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| APO-BISOPROLOL | 02256134 | 5 MG | TABLET · ORAL | APOTEX INC |
| APO-BISOPROLOL | 02256177 | 10 MG | TABLET · ORAL | APOTEX INC |
| BISOPROLOL | 02391589 | 5 MG | TABLET · ORAL | SANIS HEALTH INC |
| BISOPROLOL | 02391597 | 10 MG | TABLET · ORAL | SANIS HEALTH INC |
| BISOPROLOL TABLETS | 02495562 | 5 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| BISOPROLOL TABLETS | 02495570 | 10 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| JAMP BISOPROLOL | 02518791 | 10 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| JAMP BISOPROLOL | 02518805 | 5 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| MINT-BISOPROLOL | 02465612 | 5 MG | TABLET · ORAL | MINT PHARMACEUTICALS INC |
| MINT-BISOPROLOL | 02465620 | 10 MG | TABLET · ORAL | MINT PHARMACEUTICALS INC |
| NB-BISOPROLOL TABLETS | 02558556 | 5 MG | TABLET · ORAL | NB PHARMA INC. |
| NB-BISOPROLOL TABLETS | 02558564 | 10 MG | TABLET · ORAL | NB PHARMA INC. |
| PRO-BISOPROLOL | 02306999 | 5 MG | TABLET · ORAL | PRO DOC LIMITEE |
| PRO-BISOPROLOL | 02307006 | 10 MG | TABLET · ORAL | PRO DOC LIMITEE |
| PRZ-BISOPROLOL | 02541394 | 5 MG | TABLET · ORAL | PHARMARIS CANADA INC |
| PRZ-BISOPROLOL | 02541408 | 10 MG | TABLET · ORAL | PHARMARIS CANADA INC |
| SANDOZ BISOPROLOL TABLETS | 02494035 | 5 MG | TABLET · ORAL | SANDOZ CANADA INCORPORATED |
| SANDOZ BISOPROLOL TABLETS | 02494043 | 10 MG | TABLET · ORAL | SANDOZ CANADA INCORPORATED |
| SANDOZ BISOPROLOL TABLETS | 02544245 | 1.25 MG | TABLET · ORAL | SANDOZ CANADA INCORPORATED |
| SANDOZ BISOPROLOL TABLETS | 02544253 | 2.5 MG | TABLET · ORAL | SANDOZ CANADA INCORPORATED |
| TEVA-BISOPROLOL | 02267470 | 5 MG | TABLET · ORAL | TEVA CANADA LIMITED |
| TEVA-BISOPROLOL | 02267489 | 10 MG | TABLET · ORAL | TEVA CANADA LIMITED |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | BISOPROLOL FUMARATE 10 MG TAB | $0.16028 | per EA | 23 Sep 2026 |
| US NADAC | BISOPROLOL FUMARATE 2.5 MG TAB | $2.51999 | per EA | 23 Sep 2026 |
| US NADAC | BISOPROLOL FUMARATE 5 MG TAB | $0.11419 | per EA | 23 Sep 2026 |
| NHS Drug Tariff | Bisoprolol 1.25mg tablets | £3.82 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Bisoprolol 10mg tablets | £0.81 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Bisoprolol 2.5mg tablets | £1.00 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Bisoprolol 3.75mg tablets | £0.83 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Bisoprolol 5mg tablets | £0.83 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Bisoprolol 7.5mg tablets | £0.88 | 28 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 12.1. Antianginal medicines · core
Angina pectoris
Oral > Solid: 1.25 mg; 5 mg - 12.3. Antihypertensive medicines · core
Essential hypertension
Oral > Solid: 1.25 mg; 5 mg - 12.2. Antiarrhythmic medicines · core
Cardiac arrhythmia
Oral > Solid: 1.25 mg; 5 mg - 12.4. Medicines used in heart failure · core
Heart failure
Oral > Solid: 1.25 mg; 5 mg
Safety signals and safety-related labeling changes
- US FDA 24 Jul 2026 ZIAC — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Adverse Reactions; Patient Counseling Information / Patient Information / Medication Guide - EMA PRAC 17 Apr 2020 PRAC signal: Angioedema
Action for MAH: update of the product information: No
Combinations containing Bisoprolol
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.