Is Cyclizine approved by the US FDA?

Drugs@FDA lists 1 application product line for Cyclizine, including MAREZINE (Discontinued).

Is Cyclizine authorised in the United Kingdom?

The MHRA category lists of UK marketing authorisations include 15 products containing Cyclizine, including CYCLIZINE HYDROCHLORIDE 50 MG TABLETS; CYCLIZINE HYDROCHLORIDE 50MG TABLETS; CYCLIZINE LACTATE 50 MG/ ML SOLUTION FOR INJECTION; CYCLIZINE LACTATE 50 MG/ML INJECTION; CYCLIZINE LACTATE 50 MG/ML SOLUTION FOR INJECTION; CYCLIZINE LACTATE 50MG/ML INJECTION.

Is Cyclizine on the WHO Model List of Essential Medicines?

Yes — 2.3. Medicines for other common symptoms in palliative care (core list): Palliative care.

Active substance

Cyclizine

US FDA 1
UK MHRA 15
NHS prices 2
WHO EML 1

Open in the medicines table

US FDA United States — FDA approvals (Drugs@FDA)

Product	Strength	Form · route	Applicant	Status	First approved
MAREZINE	50MG/ML	injectable · injection	GLAXOSMITHKLINE	Discontinued	24 Sep 1954

UK MHRA United Kingdom — marketing authorisations

Product	Authorisation	Holder	Legal status
CYCLIZINE HYDROCHLORIDE 50 MG TABLETS	PL 20072/0241	AMDIPHARM UK LIMITED	P
CYCLIZINE HYDROCHLORIDE 50 MG TABLETS	PL 25298/0046	BROWN & BURK UK LIMITED	P
CYCLIZINE HYDROCHLORIDE 50MG TABLETS	PL 15764/0135	STRANDHAVEN LIMITED	P
CYCLIZINE HYDROCHLORIDE 50MG TABLETS	PL 20117/0216	MORNINGSIDE HEALTHCARE LIMITED	P
CYCLIZINE LACTATE 50 MG/ ML SOLUTION FOR INJECTION	PL 25298/0314	BROWN & BURK UK LIMITED	POM
CYCLIZINE LACTATE 50 MG/ML INJECTION	PL 20072/0010	AMDIPHARM UK LIMITED	POM
CYCLIZINE LACTATE 50 MG/ML INJECTION	PL 20117/0314	MORNINGSIDE HEALTHCARE LIMITED	POM
CYCLIZINE LACTATE 50 MG/ML SOLUTION FOR INJECTION	PL 01502/0104	HAMELN PHARMA LTD	POM
CYCLIZINE LACTATE 50 MG/ML SOLUTION FOR INJECTION	PL 01883/0270	MACARTHYS LABORATORIES LIMITED	POM
CYCLIZINE LACTATE 50 MG/ML SOLUTION FOR INJECTION	PL 39280/0012	SYNCHRONY PHARMA LIMITED	POM
CYCLIZINE LACTATE 50 MG/ML SOLUTION FOR INJECTION	PL 56854/0020	ORBIT PHARMA LIMITED	POM
CYCLIZINE LACTATE 50MG/ML INJECTION	PL 35104/0021	PHOENIX LABS UNLIMITED COMPANY	POM
CYCLIZINE LACTATE 50MG/ML SOLUTION FOR INJECTION	PL 15764/0209	STRANDHAVEN LIMITED	POM
VALOID 50MG TABLETS	PL 20072/0241	AMDIPHARM UK LIMITED	P
VALOID INJECTION	PL 20072/0010	AMDIPHARM UK LIMITED	POM

Prices — United States and England

Source	Product as listed	Price	Unit / pack	Date
NHS Drug Tariff	Cyclizine 50mg tablets	£3.09	100 tablet	1 Oct 2026
NHS Drug Tariff	Cyclizine 50mg/1ml solution for injection ampoules	£3.24	5 ampoule	1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

2.3. Medicines for other common symptoms in palliative care · core
Palliative care
Parenteral > General injections > unspecified: 50 mg per mL (lactate) (EMLc) | Oral > Solid > tablet: 50 mg (hydrochloride) (EMLc)

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), MHRA category lists of UK marketing authorisations (Open Government Licence v3.0), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.