Active substance
Demeclocycline
- US FDA 8
- UK MHRA 4
- US price lines 2
- NHS prices 2
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| DEMECLOCYCLINE HYDROCHLORIDE | 150MG; 300MG | tablet · oral | AMNEAL PHARM | Prescription | 27 Feb 2008 |
| DEMECLOCYCLINE HYDROCHLORIDE | 150MG; 300MG | tablet · oral | EPIC PHARMA LLC | Prescription | 1 Dec 2008 |
| DEMECLOCYCLINE HYDROCHLORIDE | 150MG; 300MG | tablet · oral | EPIC PHARMA LLC | Prescription | 18 Aug 2015 |
| DECLOMYCIN | 150MG | capsule · oral | LEDERLE | Discontinued | 14 Jan 1960 |
| DECLOMYCIN | 75MG/5ML | syrup · oral | LEDERLE | Discontinued | 14 Nov 1960 |
| DECLOMYCIN | 75MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 150MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 300MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | COREPHARMA | Discontinued | 22 Sep 1964 |
| DEMECLOCYCLINE HYDROCHLORIDE | 150MG; 300MG | tablet · oral | IMPAX LABS | Discontinued | 22 Mar 2004 |
| DEMECLOCYCLINE HYDROCHLORIDE | 150MG; 300MG | tablet · oral | BARR | Discontinued | 13 Dec 2004 |
UK MHRA United Kingdom — marketing authorisations
| Product | Authorisation | Holder | Legal status |
|---|---|---|---|
| DEMECLOCYCLINE HYDROCHLORIDE 150MG CAPSULES | PL 12762/0154 | MERCURY PHARMACEUTICALS LIMITED | POM |
| DEMECLOCYCLINE HYDROCHLORIDE DAWA 150 MG CAPSULES | PL 30684/0304 | DAWA LIMITED | POM |
| DEMECLOCYCLINE HYDROCHLORIDE DAWA 300MG CAPSULES | PL 30684/0305 | DAWA LIMITED | POM |
| LEDERMYCIN CAPSULES 150MG | PL 12762/0154 | MERCURY PHARMACEUTICALS LIMITED | POM |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | DEMECLOCYCLINE 150 MG TABLET | $2.27261 | per EA | 23 Sep 2026 |
| US NADAC | DEMECLOCYCLINE 300 MG TABLET | $3.04571 | per EA | 23 Sep 2026 |
| NHS Drug Tariff | Demeclocycline 150mg capsules | £238.41 | 28 capsule | 1 Oct 2026 |
| NHS Drug Tariff | Demeclocycline 300mg capsules | £452.98 | 28 capsule | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), MHRA category lists of UK marketing authorisations (Open Government Licence v3.0), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.