Regulatory PathRegulatory requirements compared

Active substance

Dihydrocodeine

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
NHS Drug TariffDihydrocodeine 120mg modified-release tablets£19.7156 tablet1 Oct 2026
NHS Drug TariffDihydrocodeine 30mg tablets£1.8228 tablet1 Oct 2026
NHS Drug TariffDihydrocodeine 30mg tablets£6.50100 tablet1 Oct 2026
NHS Drug TariffDihydrocodeine 60mg modified-release tablets£9.8856 tablet1 Oct 2026
NHS Drug TariffDihydrocodeine 90mg modified-release tablets£16.4556 tablet1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Safety signals and safety-related labeling changes

  • US FDA 22 Dec 2025 SYNALGOS-DC — safety-related labeling change
    Labeling sections changed: Boxed Warning; Contraindications; Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide

All safety entries for dihydrocodeine →

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.