Active substance
Dorzolamide
- SFDA 4
- US FDA 15
- Health Canada 4
- US price lines 1
- NHS prices 3
- Safety 3
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| TRUSOPT | 2 % | Eye drops, solution · Ocular use | 1 Dropper Container | SAR 39.15 | NCE · Prescription | MUNDIPHARMA PTY LTD | Valid |
| XOLA OPTHALMIC SOLUTION | 2 % | Eye drops, solution · Ophthalmic use | 1 Dropper Container | SAR 37.00 | Generic · Prescription | Jamjoom Pharmaceuticals Factory Company | Valid |
| ZOMIDOR 2% EYE DROPS | 2 % | Eye drops, solution · Ophthalmic use | 1 Dropper Container | SAR 29.90 | Generic · Prescription | RIYADH PHARMA | Valid |
| TRUSOPT | 2 % | Eye drops, solution · Ophthalmic use | 1 Dropper Container | SAR 58.65 | NCE · Prescription | MERCK SHARP & DOHME | Withdrawn by MAH · Not Marketed |
Indications — CHI Daman Drug Formulary
OPEN ANGLE GLUCOMA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | RUBICON RESEARCH | Prescription | 28 Oct 2008 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | SANDOZ | Prescription | 6 Nov 2008 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | SANDOZ | Prescription | 13 Apr 2009 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | BAUSCH AND LOMB | Prescription | 25 Jun 2009 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | REGCON HOLDINGS | Prescription | 11 Sep 2014 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | FDC LTD | Prescription | 24 Jan 2019 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | ALEMBIC | Prescription | 9 Aug 2019 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | MICRO LABS | Prescription | 8 Nov 2019 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | GLAND | Prescription | 27 Jan 2022 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | SOMERSET THERAPS LLC | Prescription | 11 Feb 2025 |
| TRUSOPT | EQ 2% BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | solution/drops · ophthalmic | MSD SUB MERCK | Discontinued | 9 Dec 1994 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | HIKMA PHARMS | Discontinued | 28 Oct 2008 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | TEVA PHARMS | Discontinued | 4 Dec 2008 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | AM REGENT | Discontinued | 18 Nov 2009 |
| DORZOLAMIDE HYDROCHLORIDE | EQ 2% BASE | solution/drops · ophthalmic | ZAMBON SPA | Discontinued | 4 Dec 2013 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| DORZOLAMIDE | 02522373 | 20 MG / ML | SOLUTION · OPHTHALMIC | JAMP PHARMA CORPORATION |
| DORZOLAMIDE | 02561573 | 2 % / W/V | SOLUTION · OPHTHALMIC | STERI-MED PHARMA INC. |
| MED-DORZOLAMIDE | 02457210 | 2 % / W/V | SOLUTION · OPHTHALMIC | GENERIC MEDICAL PARTNERS INC |
| SANDOZ DORZOLAMIDE | 02316307 | 2 % | SOLUTION · OPHTHALMIC | SANDOZ CANADA INCORPORATED |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | DORZOLAMIDE HCL 2% EYE DROPS | $0.83485 | per ML | 23 Sep 2026 |
| NHS Drug Tariff | Dorzolamide 20mg/ml eye drops | £2.19 | 5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Dorzolamide 20mg/ml eye drops 0.2ml unit dose preservative free | £24.18 | 60 unit dose | 1 Oct 2026 |
| NHS Drug Tariff | Dorzolamide 20mg/ml eye drops preservative free | £7.08 | 5 ml | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Safety signals and safety-related labeling changes
- US FDA 9 Apr 2026 COSOPT PF — safety-related labeling change
Labeling sections changed: Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 21 Dec 2020 TRUSOPT — safety-related labeling change
Labeling sections changed: Use in Specific Populations - US FDA 23 Nov 2020 COSOPT — safety-related labeling change
Labeling sections changed: Patient Counseling Information / Patient Information / Medication Guide
Combinations containing Dorzolamide
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.