Active substances
Drospirenone + Ethinylestradiol + Levomefolate
- US FDA 6
- Health Canada 1
- US price lines 2
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| BEYAZ | 3MG,N/A;0.02MG,N/A;0.451MG,0.451MG | tablet · oral | BAYER HLTHCARE | Prescription | 24 Sep 2010 |
| SAFYRAL | 3MG,N/A;0.03MG,N/A;0.451MG,0.451MG | tablet · oral | BAYER HLTHCARE | Prescription | 16 Dec 2010 |
| DROSPIRENONE, ETHINYL ESTRADIOL AND LEVOMEFOLATE CALCIUM | 3MG,N/A;0.02MG,N/A;0.451MG,0.451MG | tablet · oral | WATSON LABS INC | Prescription | 11 Oct 2016 |
| DROSPIRENONE, ETHINYL ESTRADIOL AND LEVOMEFOLATE CALCIUM | 3MG,N/A;0.03MG,N/A;0.451MG,0.451MG | tablet · oral | WATSON LABS INC | Prescription | 11 Oct 2016 |
| TYDEMY | 3MG,N/A;0.03MG,N/A;0.451MG,0.451MG | tablet · oral | LUPIN | Prescription | 12 Dec 2017 |
| DROSPIRENONE, ETHINYL ESTRADIOL AND LEVOMEFOLATE CALCIUM | 3MG,N/A;0.02MG,N/A;0.451MG,0.451MG | tablet · oral | LUPIN | Prescription | 13 Jun 2018 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| YAZ PLUS | 02387433 | 0.451 MG; 3.00 MG; 0.02 MG | TABLET · ORAL | BAYER INC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | BEYAZ 28 TABLET | $8.29785 | per EA | 23 Sep 2026 |
| US NADAC | TYDEMY 3-0.03-0.451 MG TABLET | $2.95972 | per EA | 23 Sep 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Components
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.