Active substance
Ephedrine
- SFDA 2
- US FDA 24
- Health Canada 1
- NHS prices 2
- WHO EML 1
- Safety 3
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| EPHEDRINE HYDROCHLORIDE 30 mg/ml solution for injction | 30 mg/ml | Solution for injection · Parenteral use | 10 Ampoule | SAR 49.00 | Generic · Prescription | MACARTHYS LABORATORIES Ltd T/A MARTINDALE PHARMACEUTICALS | Valid |
| Ephedrine 3 mg/ml , solution for injection in pre-filled syringe | 3 mg/ml | Solution for injection in pre-filled syringe · Intravenous use | 10 Pre-filled syringe | SAR 273.05 | NCE · Prescription | AGUETTANT LABORATORIES | Valid |
Indications — CHI Daman Drug Formulary
ANESTHESIA-SUPPORTIVE AGENTS/ CARDIAC ARREST, CARDIOVASCULAR EMERGENCIES AND/OR DYSRHYTHMIAS; HYPOTENSION
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| AKOVAZ | 50MG/ML (50MG/ML); 25MG/5ML (5MG/ML) | solution · intravenous | EXELA PHARMA | Prescription | 29 Apr 2016 |
| CORPHEDRA | 50MG/ML (50MG/ML) | solution · intravenous | PH HEALTH | Prescription | 27 Jan 2017 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | SANDOZ | Prescription | 23 Aug 2017 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | AMNEAL | Prescription | 23 Oct 2019 |
| EMERPHED | 50MG/10ML (5MG/ML); 25MG/5ML (5MG/ML) | solution · intravenous | NEXUS | Prescription | 17 Apr 2020 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | FRESENIUS KABI USA | Prescription | 4 Aug 2020 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | DR REDDYS | Prescription | 3 Oct 2020 |
| EPHEDRINE SULFATE | 50MG/10ML (5MG/ML); 25MG/5ML (5MG/ML) | solution · intravenous | PH HEALTH | Prescription | 16 Oct 2020 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | HIKMA PHARMS | Prescription | 15 Dec 2020 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | EUGIA PHARMA | Prescription | 14 Jun 2021 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | GLAND | Prescription | 25 Feb 2022 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | MANKIND PHARMA | Prescription | 14 Apr 2022 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | XIROMED | Prescription | 21 Apr 2022 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | SAGENT PHARMS INC | Prescription | 9 Mar 2023 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | CAPLIN | Prescription | 18 Jul 2024 |
| EPHEDRINE SULFATE | 25MG/5ML (5MG/ML) | solution · intravenous | HIKMA | Prescription | 11 Oct 2024 |
| EPHEDRINE SULFATE | 50MG/10ML (5MG/ML) | solution · intravenous | GLAND | Prescription | 16 Jan 2025 |
| EPHEDRINE SULFATE | 25MG/5ML (5MG/ML); 50MG/10ML (5MG/ML) | solution · intravenous | FRESENIUS KABI USA | Prescription | 11 Mar 2025 |
| EPHEDRINE SULFATE | 50MG/10ML (5MG/ML) | solution · intravenous | FRESENIUS KABI USA | Prescription | 19 Mar 2026 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | BAXTER HLTHCARE CORP | Prescription | 8 Jul 2026 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | RENEW PHARMS | Discontinued | 1 Mar 2017 |
| REZIPRES | 23.5MG/5ML (4.7MG/ML); 47MG/ML (47MG/ML); 47MG/5ML (9.4MG/ML); 47MG/10ML (4.7MG/ML) | solution · intravenous | DR REDDYS LABS SA | Discontinued | 14 Jun 2021 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | ZYDUS PHARMS | Discontinued | 16 May 2023 |
| EPHEDRINE SULFATE | 50MG/ML (50MG/ML) | solution · intravenous | CIVICA | Discontinued | 23 Dec 2025 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| EPHEDRINE SULFATE INJECTION USP | 00876534 | 50 MG / ML | SOLUTION · INTRAVENOUS; SUBCUTANEOUS; INTRAMUSCULAR | SANDOZ CANADA INCORPORATED |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| NHS Drug Tariff | Ephedrine hydrochloride 15mg tablets | £125.00 | 28 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Ephedrine hydrochloride 30mg tablets | £180.00 | 28 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 1.2. Local anaesthetics · complementary
Cardiac complications of anaesthesia during labour or delivery
Parenteral > Locoregional injections > Spinal anaesthesia: 30 mg per mL in 1 mL ampoule (ephedrine hydrochloride)
Safety signals and safety-related labeling changes
- US FDA 15 Aug 2024 EMERPHED — safety-related labeling change
Labeling sections changed: Drug Interactions; Use in Specific Populations - US FDA 10 Jun 2024 EPHEDRINE SULFATE — safety-related labeling change
Labeling sections changed: Use in Specific Populations - US FDA 8 Apr 2020 AKOVAZ — safety-related labeling change
Labeling sections changed: Use in Specific Populations
Combinations containing Ephedrine
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.