Regulatory PathRegulatory requirements compared

Active substance

Ergocalciferol

Open in the medicines table

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
DRISDOL50,000 IUcapsule · oralESJAY PHARMAPrescription11 Jan 1941
VITAMIN D50,000 IUcapsule · oralBIONPHARMAPrescription16 Oct 1978
ERGOCALCIFEROL50,000 IUcapsule · oralCHARTWELL RXPrescription20 May 2009
ERGOCALCIFEROL50,000 IUcapsule · oralONESOURCEPrescription3 Aug 2010
ERGOCALCIFEROL50,000 IUcapsule · oralPURACAP PHARM LLCPrescription7 Dec 2018
VITAMIN D50,000 IUcapsule · oralWEST WARDDiscontinued26 Mar 1973
DELTALIN50,000 IUcapsule · oralLILLYDiscontinued12 Jun 1973
VITAMIN D50,000 IUcapsule · oralIMPAX LABSDiscontinued13 Jul 1973
VITAMIN D50,000 IUcapsule · oralCHARTWELL MOLECULARDiscontinued26 Sep 1974
ERGOCALCIFEROL50,000 IUcapsule · oralSUN PHARM INDS INCDiscontinued29 Dec 2009
ERGOCALCIFEROL50,000 IUcapsule · oralSIGMAPHARM LABS LLCDiscontinued14 Jul 2010
VITAMIN D50,000 IUcapsule · oralCHASE CHEMDiscontinued
VITAMIN D50,000 IUcapsule · oralEVERYLIFEDiscontinued
VITAMIN D50,000 IUcapsule · oralVITARINEDiscontinued

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACERGOCALCIFEROL 1.25 MG CAPSULE$0.11361per EA23 Sep 2026
NHS Drug TariffErgocalciferol 300,000units/1ml solution for injection ampoules£70.155 ampoule1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

  • 27. Vitamins and minerals · core
    Therapeutic equivalent to colecalciferol for Calcium deficiency; Therapeutic equivalent to colecalciferol for Vitamin D deficiency; Calcium deficiency; Vitamin D deficiency
    Oral > Liquid: 250 µg per mL (10 000 IU per mL) | Oral > Solid: 1.25 mg (50 000 IU) | Oral > Liquid: 250 µg per mL (10 000 IU per mL) (EML) | Oral > Solid: 1.25 mg (50 000 IU) (EML)

Safety signals and safety-related labeling changes

All safety entries for ergocalciferol →

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.