Active substance
Lamotrigine
- SFDA 22
- US FDA 67
- Health Canada 29
- US price lines 36
- NHS prices 8
- WHO EML 1
- Safety 8
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| LAMICTAL | 50 mg | Tablet · Oral use | 30 Blister | SAR 57.20 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| LAMICTAL | 25 mg | Tablet · Oral use | 30 Blister | SAR 32.65 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| LAMICTAL | 5 mg | Chewable tablet · Oral use | 28 Blister | SAR 11.10 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| LAMICTAL | 25 mg | Chewable tablet · Oral use | 56 Blister | SAR 50.95 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| LAMICTAL | 100 mg | Chewable tablet · Oral use | 56 Blister | SAR 169.50 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| LAMIRA 100 mg TABLET | 100 mg | Tablet · Oral use | 30 Blister | SAR 74.15 | Generic · Prescription | SPIMACO ADDWAEIH | Valid |
| LAMIRA 25 mg TABLET | 25 mg | Tablet · Oral use | 30 Blister | SAR 25.85 | Generic · Prescription | SPIMACO ADDWAEIH | Valid |
| LAMIRA 50 mg TABLET | 50 mg | Tablet · Oral use | 30 Blister | SAR 41.00 | Generic · Prescription | SPIMACO ADDWAEIH | Valid |
| LAMOTRIX 100MG TABLET | 100 mg | Tablet · Oral use | 30 Blister | SAR 74.15 | Generic · Prescription | MEDOCHEMIE LTD PHARMACEUTICAL INDUSTRY | Valid |
| LAMOTRIX 25MG TABLET | 25 mg | Tablet · Oral use | 30 Blister | SAR 25.85 | Generic · Prescription | MEDOCHEMIE LTD PHARMACEUTICAL INDUSTRY | Valid |
| LAMOTRIX 50MG TABLET | 50 mg | Tablet · Oral use | 30 Blister | SAR 41.00 | Generic · Prescription | MEDOCHEMIE LTD PHARMACEUTICAL INDUSTRY | Valid |
| LOXOL 100MG TABLET | 100 mg | Tablet · Oral use | 30 Blister | SAR 82.40 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| LOXOL 200MG TABLET | 200 mg | Tablet · Oral use | 30 Blister | SAR 135.15 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| LOXOL 25MG TABLET | 25 mg | Tablet · Oral use | 30 Blister | SAR 28.75 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| LOXOL 50MG TABLET | 50 mg | Tablet · Oral use | 30 Blister | SAR 45.55 | Generic · Prescription | Jazeera Pharmaceutical Industries (JPI) | Valid |
| Lamictal | 100 mg | Tablet · Oral use | 30 Blister | SAR 91.30 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| Lamotrine | 25 mg | Tablet · Oral use | 30 Blister | SAR 23.25 | Generic · Prescription | Apex Pharma | Valid |
| Lamotrine | 100 mg | Tablet · Oral use | 30 Blister | SAR 66.75 | Generic · Prescription | Apex Pharma | Valid |
| Lamotrine | 50 mg | Tablet · Oral use | 30 Blister | SAR 33.35 | Generic · Prescription | Apex Pharma | Valid |
| SEIZET 100 mg Chewable/Dispersible Tablet | 100 mg | Chewable/dispersible tablet · Oral use | 30 Blister | SAR 66.75 | Generic · Prescription | MS Pharma Saudi (MSPS) | Valid |
| SEIZET 25 mg Chewable/Dispersible Tablet | 25 mg | Chewable/dispersible tablet · Oral use | 30 Blister | SAR 23.25 | Generic · Prescription | MS Pharma Saudi (MSPS) | Valid |
| LAMICTAL | 25 mg | Chewable tablet · Oral use | 14 Blister | SAR 18.10 | NCE · Prescription | GLAXO SAUDI ARABIA | Withdrawn by MAH · Not Marketed |
Indications — CHI Daman Drug Formulary
ACUTE BIPOLAR I DEPRESSION; ANXIETY DISORDERS; BIPOLAR I DISORDER MAINTENANCE; JUVENILE MYOCLONIC SEIZURES; LENNOX GASTAUT SYNDROME AND TONIC OR ATONIC SEIZURES; NEUROPATHIC PAIN; PAIN MANAGEMENT IN CANCER PATIENTS; TRIGEMINAL NEURALGIA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| LAMICTAL | 100MG; 150MG; 200MG; 25MG | tablet · oral | GLAXOSMITHKLINE LLC | Prescription | 27 Dec 1994 |
| LAMICTAL CD | 5MG; 25MG; 2MG | tablet, for suspension · oral | GLAXOSMITHKLINE LLC | Prescription | 24 Aug 1998 |
| LAMOTRIGINE | 5MG; 25MG | tablet, for suspension · oral | DR REDDYS LABS LTD | Prescription | 22 Jan 2009 |
| LAMOTRIGINE | 2MG; 5MG; 25MG | tablet, for suspension · oral | WATSON LABS | Prescription | 22 Jan 2009 |
| LAMOTRIGINE | 2MG | tablet, chewable · oral | ZYDUS PHARMS USA INC | Prescription | 22 Jan 2009 |
| LAMOTRIGINE | 5MG; 25MG | tablet, for suspension · oral | ZYDUS PHARMS USA INC | Prescription | 22 Jan 2009 |
| LAMOTRIGINE | 2MG | tablet · oral | CHARTWELL RX | Prescription | 22 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | DR REDDYS LABS LTD | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 50MG; 100MG; 150MG; 200MG; 250MG | tablet · oral | ZYDUS PHARMS USA | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | TARO PHARM INDS | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | RUBICON RESEARCH | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | TORRENT PHARMS | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | AUROBINDO PHARMA | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | JUBILANT CADISTA | Prescription | 27 Jan 2009 |
| LAMOTRIGINE | 5MG; 25MG | tablet, for suspension · oral | GLENMARK PHARMS LTD | Prescription | 19 Feb 2009 |
| LAMICTAL ODT | 25MG; 50MG; 100MG; 200MG | tablet, orally disintegrating · oral | GLAXOSMITHKLINE LLC | Prescription | 8 May 2009 |
| LAMICTAL XR | 25MG; 50MG; 100MG; 200MG; 300MG; 250MG | tablet, extended release · oral | GLAXOSMITHKLINE LLC | Prescription | 29 May 2009 |
| LAMOTRIGINE | 5MG | tablet · oral | AUROBINDO PHARMA | Prescription | 4 Nov 2009 |
| LAMOTRIGINE | 5MG; 25MG | tablet, for suspension · oral | AUROBINDO PHARMA | Prescription | 4 Nov 2009 |
| LAMICTAL XR | 25MG; 50MG; 100MG; 200MG | tablet, extended release · oral | SMITHKLINE BEECHAM | Prescription | 29 Jan 2010 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | ALEMBIC PHARMS LTD | Prescription | 13 Jan 2011 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | UNICHEM LABS LTD | Prescription | 6 Oct 2011 |
| LAMOTRIGINE | 25MG; 100MG; 150MG; 200MG | tablet · oral | GLENMARK PHARMS LTD | Prescription | 4 May 2012 |
| LAMOTRIGINE | 25MG; 50MG; 100MG; 200MG; 250MG; 300MG | tablet, extended release · oral | PH HEALTH | Prescription | 26 Dec 2012 |
| LAMOTRIGINE | 25MG; 50MG; 100MG; 200MG; 300MG | tablet, extended release · oral | SCIEGEN PHARMS | Prescription | 4 Jan 2013 |
42 more — full table
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| AG-LAMOTRIGINE | 02543710 | 25 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| AG-LAMOTRIGINE | 02543729 | 100 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| AG-LAMOTRIGINE | 02543737 | 150 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| APO-LAMOTRIGINE | 02245208 | 25 MG | TABLET · ORAL | APOTEX INC |
| APO-LAMOTRIGINE | 02245209 | 100 MG | TABLET · ORAL | APOTEX INC |
| APO-LAMOTRIGINE | 02245210 | 150 MG | TABLET · ORAL | APOTEX INC |
| AURO-LAMOTRIGINE | 02381354 | 25 MG | TABLET · ORAL | AURO PHARMA INC |
| AURO-LAMOTRIGINE | 02381362 | 100 MG | TABLET · ORAL | AURO PHARMA INC |
| AURO-LAMOTRIGINE | 02381370 | 150 MG | TABLET · ORAL | AURO PHARMA INC |
| JAMP LAMOTRIGINE | 02542730 | 25 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| JAMP LAMOTRIGINE | 02542749 | 100 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| JAMP LAMOTRIGINE | 02542757 | 150 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| LAMICTAL | 02142082 | 25 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| LAMICTAL | 02142104 | 100 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| LAMICTAL | 02142112 | 150 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| LAMICTAL | 02240115 | 5 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| LAMICTAL | 02243803 | 2 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| LAMOTRIGINE | 02343010 | 25 MG | TABLET · ORAL | SANIS HEALTH INC |
| LAMOTRIGINE | 02343029 | 100 MG | TABLET · ORAL | SANIS HEALTH INC |
| LAMOTRIGINE | 02343037 | 150 MG | TABLET · ORAL | SANIS HEALTH INC |
| LAMOTRIGINE | 02428202 | 25 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| LAMOTRIGINE | 02428210 | 100 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| LAMOTRIGINE | 02428229 | 150 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| LAMOTRIGINE-100 | 02302985 | 100 MG | TABLET · ORAL | PRO DOC LIMITEE |
| LAMOTRIGINE-150 | 02302993 | 150 MG | TABLET · ORAL | PRO DOC LIMITEE |
4 more — full table
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | LAMICTAL 100 MG TABLET | $10.91795 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL 150 MG TABLET | $11.4684 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL 200 MG TABLET | $12.05122 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL 25 MG DISPER TABLET | $11.18289 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL 25 MG TABLET | $10.29501 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL ODT 100 MG TABLET | $14.63582 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL ODT 200 MG TABLET | $17.48893 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL ODT 25 MG TABLET | $12.81313 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL ODT 50 MG TABLET | $13.65287 | per EA | 20 May 2026 |
| US NADAC | LAMICTAL XR 100 MG TABLET | $30.40041 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL XR 200 MG TABLET | $32.33073 | per EA | 23 Sep 2026 |
| US NADAC | LAMICTAL XR 25 MG TABLET | $14.2042 | per EA | 23 Sep 2026 |
| NHS Drug Tariff | Lamotrigine 100mg dispersible tablets sugar free | £15.19 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 100mg tablets | £2.55 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 200mg tablets | £3.06 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 25mg dispersible tablets sugar free | £18.11 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 25mg tablets | £1.97 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 2mg dispersible tablets sugar free | £18.81 | 30 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 50mg tablets | £2.38 | 56 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Lamotrigine 5mg dispersible tablets sugar free | £13.18 | 28 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 5.1.1. Antiseizure medicines · core
Epilepsy or seizures
Oral > Solid: 25 mg tablet; 50 mg tablet; 100 mg tablet; 200 mg tablet; 2 mg tablet (chewable, dispersible); 5 mg tablet (chewable, dispersible); 25 mg tablet (chewable, dispersible); 50 mg tablet (chewable, dispersible); 100 mg tablet (chewable, dispersible); 200 mg tablet (chewable, dispersible)
Safety signals and safety-related labeling changes
- US FDA 17 Jul 2026 SUBVENITE — safety-related labeling change
Labeling sections changed: Boxed Warning; Warnings and Precautions; Adverse Reactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 10 Oct 2025 LAMICTAL — safety-related labeling change
Labeling sections changed: Boxed Warning; Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 10 Oct 2025 LAMICTAL CD — safety-related labeling change
Labeling sections changed: Boxed Warning; Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 10 Oct 2025 LAMICTAL ODT — safety-related labeling change
Labeling sections changed: Boxed Warning; Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 10 Oct 2025 LAMICTAL XR — safety-related labeling change
Labeling sections changed: Boxed Warning; Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - EMA PRAC 29 Oct 2020 PRAC signal: Photosensitivity
Action for MAH: update of the product information: Yes - EMA PRAC 12 Mar 2020 PRAC signal: Photosensitivity
Action for MAH: update of the product information: No - EMA PRAC 5 Dec 2013 PRAC signal: Drug reaction with eosinophilia and systemic symptoms (DRESS)
Action for MAH: update of the product information: No
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.