Regulatory PathRegulatory requirements compared

Active substance

Liothyronine

Open in the medicines table

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
CYTOMELEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralKING PHARMSPrescription8 May 1956
LIOTHYRONINE SODIUMEQ 0.01MG BASE/MLinjectable · injectionXGEN PHARMSPrescription17 Aug 2005
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralDR REDDYS LABS SAPrescription20 Mar 2009
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralSIGMAPHARM LABS LLCPrescription29 Nov 2012
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralSUN PHARMPrescription20 Apr 2016
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralTEVA PHARMS USAPrescription26 Oct 2018
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralZYDUS LIFESCIENCESPrescription22 Jan 2021
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralBIOCON PHARMAPrescription6 Feb 2024
LIOTHYRONINE SODIUMEQ 0.025MG BASEtablet · oralWATSON LABSDiscontinued25 Jan 1982
LIOTHYRONINE SODIUMEQ 0.05MG BASEtablet · oralWATSON LABSDiscontinued3 Feb 1982
TRIOSTATEQ 0.01MG BASE/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**injectable · injectionPH HEALTHDiscontinued31 Dec 1991
LIOTHYRONINE SODIUMEQ 0.005MG BASE; EQ 0.025MG BASE; EQ 0.05MG BASEtablet · oralPHARMOBEDIENTDiscontinued14 Jul 2009

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
AURO-LIOTHYRONINE025499995 MCGTABLET · ORALAURO PHARMA INC
AURO-LIOTHYRONINE0255000825 MCGTABLET · ORALAURO PHARMA INC
CYTOMEL019194585 MCGTABLET · ORALPFIZER CANADA ULC
CYTOMEL0191946625 MCGTABLET · ORALPFIZER CANADA ULC
TEVA-LIOTHYRONINE024943375 MCGTABLET · ORALTEVA CANADA LIMITED
TEVA-LIOTHYRONINE0249434525 MCGTABLET · ORALTEVA CANADA LIMITED
ZDS-LIOTHYRONINE025612985 MCGTABLET · ORALZYDUS LIFESCIENCES LIMITED
ZDS-LIOTHYRONINE0256130125 MCGTABLET · ORALZYDUS LIFESCIENCES LIMITED

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACCYTOMEL 25 MCG TABLET$0.53303per EA23 Sep 2026
US NADACCYTOMEL 5 MCG TABLET$0.3857per EA23 Sep 2026
US NADACLIOTHYRONINE SOD 25 MCG TAB$0.29408per EA23 Sep 2026
US NADACLIOTHYRONINE SOD 5 MCG TAB$0.2023per EA23 Sep 2026
US NADACLIOTHYRONINE SOD 50 MCG TAB$0.36222per EA23 Sep 2026
NHS Drug TariffLiothyronine 10microgram capsules£65.0028 capsule1 Oct 2026
NHS Drug TariffLiothyronine 10microgram tablets£152.4428 tablet1 Oct 2026
NHS Drug TariffLiothyronine 20microgram capsules£55.0028 capsule1 Oct 2026
NHS Drug TariffLiothyronine 20microgram tablets£18.8628 tablet1 Oct 2026
NHS Drug TariffLiothyronine 5microgram capsules£55.0028 capsule1 Oct 2026
NHS Drug TariffLiothyronine 5microgram tablets£35.7928 tablet1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.