Is Mepivacaine registered with the SFDA?

The SFDA human drug list (edition 4-2026, as published by the Council of Health Insurance) lists 3 valid registrations of Mepivacaine, including ISOCAINE 3 % CARTRIDGE (3 %, Solution for injection, SAR 70.70); MEDICAINE 3% CARTRIDGE (30 mg, Solution for injection in cartridge, SAR 94.60); SCANDICAINE 3% CARTRIDGE 1.8ML (3 %, Solution, SAR 99.60).

Is Mepivacaine approved by the US FDA?

Drugs@FDA lists 16 application product lines for Mepivacaine, including SCANDONEST PLAIN (Prescription); POLOCAINE-MPF (Prescription); POLOCAINE (Prescription); POLOCAINE-MPF (Prescription); POLOCAINE-MPF (Prescription).

Are there safety signals or safety updates for Mepivacaine?

US FDA: 1 entry (latest 2023-12-21).

Active substance

Mepivacaine

SFDA 5
US FDA 16
Health Canada 7
Safety 1

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade name	Strength	Form · route	Pack	Public price	Type	Company	Status
ISOCAINE 3 % CARTRIDGE	3 %	Solution for injection · Dental use	50 Cartridge	SAR 70.70	Generic · Prescription	NOVOCOL	Valid
MEDICAINE 3% CARTRIDGE	30 mg	Solution for injection in cartridge · Dental use	50 Cartridge	SAR 94.60	NCE · Prescription	LES LABORATOIRES MEDIS	Valid
SCANDICAINE 3% CARTRIDGE 1.8ML	3 %	Solution · Dental use	50 Cartridge	SAR 99.60	NCE · Prescription	SEPTODENT	Valid
MEPECAINE 3% CARPULE	3 %	Solution for injection in cartridge · Dental use	50 Cartridge	SAR 50.40	Generic · Prescription	ALEXANDRIA CO.	Withdrawn by regulatory authority · Not Marketed
MEPICATON 3% CARTRIDGES (1.8)ML	3 %	Solution · Dental use	50 Cartridge	SAR 68.90	Generic · Prescription	WEIMER PHARMA	Withdrawn by regulatory authority · Not Marketed

Indications — CHI Daman Drug Formulary

ANESTHESIA

US FDA United States — FDA approvals (Drugs@FDA)

Product	Strength	Form · route	Applicant	Status	First approved
SCANDONEST PLAIN	3%	injectable · injection	DEPROCO	Prescription	10 Oct 1984
POLOCAINE-MPF	1%	injectable · injection	FRESENIUS KABI USA	Prescription	1 Dec 1986
POLOCAINE	1%	injectable · injection	FRESENIUS KABI USA	Prescription	1 Dec 1986
POLOCAINE-MPF	1.5%	injectable · injection	FRESENIUS KABI USA	Prescription	1 Dec 1986
POLOCAINE-MPF	2%	injectable · injection	FRESENIUS KABI USA	Prescription	1 Dec 1986
POLOCAINE	2%	injectable · injection	FRESENIUS KABI USA	Prescription	1 Dec 1986
CARBOCAINE	3% Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	injectable · injection	EASTMAN KODAK	Discontinued	6 Jan 1960
CARBOCAINE	1% Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons; 2% Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons; 1.5% Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	injectable · injection	HOSPIRA	Discontinued	17 May 1960
ISOCAINE HYDROCHLORIDE	3%	injectable · injection	SEPTODONT	Discontinued	17 Oct 1972
MEPIVACAINE HYDROCHLORIDE	3%	injectable · injection	BELMORA LLC	Discontinued	4 Dec 1973
ARESTOCAINE HYDROCHLORIDE	3%	injectable · injection	SOLVAY	Discontinued	17 Dec 1975
MEPIVACAINE HYDROCHLORIDE	1%	injectable · injection	INTL MEDICATION SYS	Discontinued	5 Oct 1982
POLOCAINE	3%	injectable · injection	DENTSPLY PHARM	Discontinued	21 Aug 1984
MEPIVACAINE HYDROCHLORIDE	1%	injectable · injection	WATSON LABS	Discontinued	20 Nov 1984
MEPIVACAINE HYDROCHLORIDE	2%	injectable · injection	WATSON LABS	Discontinued	20 Nov 1984
MEPIVACAINE HYDROCHLORIDE	3%	injectable · injection	HOSPIRA INC	Discontinued	28 Apr 2008

Canada Canada — marketed products (Health Canada)

Brand	DIN	Strength	Form · route	Company
3% POLOCAINE DENTAL	02330733	30 MG / ML	LIQUID · BLOCK/INFILTRATION	DENTSPLY CANADA LIMITED
CARBOCAINE 1%	02241999	10 MG / ML	SOLUTION · INTRACAUDAL; EPIDURAL	PFIZER CANADA ULC
CARBOCAINE 1%	02242000	10 MG / ML	SOLUTION · BLOCK/INFILTRATION	PFIZER CANADA ULC
CARBOCAINE 2%	02242001	20 MG / ML	SOLUTION · EPIDURAL; INTRACAUDAL	PFIZER CANADA ULC
CARBOCAINE 3%	02474174	30 MG / ML	SOLUTION · BLOCK/INFILTRATION	SEPTODONT
ISOCAINE HCL INJ 3%	00364304	30 MG / ML	SOLUTION · BLOCK/INFILTRATION	NOVOCOL PHARMACEUTICAL OF CANADA INC
SCANDONEST 3% PLAIN INJ	00479934	30 MG / ML	SOLUTION · BLOCK/INFILTRATION	SEPTODONT

Safety signals and safety-related labeling changes

US FDA 21 Dec 2023 CARBOCAINE — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Adverse Reactions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide

All safety entries for mepivacaine →

Combinations containing Mepivacaine

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.