Active substance
Midodrine
- SFDA 3
- US FDA 15
- Health Canada 10
- US price lines 3
- NHS prices 3
- Safety 1
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| GUTRON TAB 2.5 MG TAB | 2.5 mg | Tablet · Oral use | 50 Blister | SAR 16.55 | NCE · Prescription | Takeda Manufacturing Austria AG | Valid |
| GUTRON TAB 2.5 MG TAB | 2.5 mg | Tablet · Oral use | 20 Blister | SAR 8.75 | NCE · Prescription | Takeda Manufacturing Austria AG | Valid |
| GUTRON Injection* | 2.5 mg/ml | Injection · Oral use | 5 Ampoule | SAR 12.45 | NCE · Prescription | Takeda Manufacturing Austria AG | Withdrawn by MAH · Not Marketed |
Indications — CHI Daman Drug Formulary
DIALYSIS; HYPOTENSION
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | MYLAN PHARMS INC | Prescription | 10 Sep 2003 |
| ORVATEN | 2.5MG; 5MG; 10MG | tablet · oral | BEIJING YILING | Prescription | 3 Nov 2004 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | APOTEX | Prescription | 12 Sep 2006 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | PH HEALTH | Prescription | 29 Oct 2018 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | UNIQUE | Prescription | 2 Nov 2018 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | RUBICON RESEARCH | Prescription | 19 Aug 2019 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | AUROBINDO PHARMA LTD | Prescription | 10 Aug 2020 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | ZYDUS LIFESCIENCES | Prescription | 1 Sep 2020 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | XIROMED | Prescription | 1 Oct 2020 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | ALEMBIC | Prescription | 21 Jan 2021 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | NOVUGEN | Prescription | 17 Oct 2023 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | MANKIND PHARMA | Prescription | 1 Nov 2023 |
| PROAMATINE | 2.5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | tablet · oral | TAKEDA PHARMS USA | Discontinued | 6 Sep 1996 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | CHARTWELL RX | Discontinued | 11 Sep 2003 |
| MIDODRINE HYDROCHLORIDE | 2.5MG; 5MG; 10MG | tablet · oral | IMPAX PHARMS | Discontinued | 27 May 2004 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| APO-MIDODRINE | 02278677 | 2.5 MG | TABLET · ORAL | APOTEX INC |
| APO-MIDODRINE | 02278685 | 5 MG | TABLET · ORAL | APOTEX INC |
| JAMP MIDODRINE | 02517701 | 2.5 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| JAMP MIDODRINE | 02517728 | 5 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| M-MIDODRINE | 02547112 | 2.5 MG | TABLET · ORAL | MANTRA PHARMA INC |
| M-MIDODRINE | 02547120 | 5 MG | TABLET · ORAL | MANTRA PHARMA INC |
| MAR-MIDODRINE | 02473984 | 2.5 MG | TABLET · ORAL | MARCAN PHARMACEUTICALS INC |
| MAR-MIDODRINE | 02473992 | 5 MG | TABLET · ORAL | MARCAN PHARMACEUTICALS INC |
| MIDODRINE | 02533200 | 2.5 MG | TABLET · ORAL | SANIS HEALTH INC |
| MIDODRINE | 02533219 | 5 MG | TABLET · ORAL | SANIS HEALTH INC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | MIDODRINE HCL 10 MG TABLET | $0.15125 | per EA | 7 Oct 2026 |
| US NADAC | MIDODRINE HCL 2.5 MG TABLET | $0.07366 | per EA | 7 Oct 2026 |
| US NADAC | MIDODRINE HCL 5 MG TABLET | $0.11131 | per EA | 7 Oct 2026 |
| NHS Drug Tariff | Midodrine 10mg tablets | £35.00 | 100 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Midodrine 2.5mg tablets | £7.15 | 100 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Midodrine 5mg tablets | £9.67 | 100 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Safety signals and safety-related labeling changes
- US FDA 7 Feb 2017 PROAMATINE — safety-related labeling change
Labeling sections changed: Warnings and Precautions
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.