Regulatory PathRegulatory requirements compared

Active substances

Naloxone + Oxycodone

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade nameStrengthForm · routePackPublic priceTypeCompanyStatus
TARGINACT 10MG/5MG PR TABLET10,5 mg,mgFilm-coated tablet · Oral use56 BlisterSAR 110.25NCE · PrescriptionNapp pharmaceuticals limitedValid
TARGINACT 20MG/10MG PR TABLET20,10 mg,mgProlonged-release tablet · Oral use56 BlisterSAR 220.55NCE · PrescriptionNapp pharmaceuticals limitedValid
TARGINACT 40MG/20MG PR TABLET40,20 mg,mgProlonged-release tablet · Oral use56 BlisterSAR 421.95NCE · PrescriptionNapp pharmaceuticals limitedValid
Indications — CHI Daman Drug Formulary

DIABETIC NEUROPATHY; ENDOMETRIOSIS; LOW BACK PAIN; NEUROPATHIC PAIN; OSTEOARTHRITIS; PAIN MANAGEMENT IN CANCER PATIENTS; POST-HERPETIC NEURALGIA; POSTOPERATIVE PAIN; RENAL AND URETERIC STONES

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
TARGINIQ5MG;10MG; 10MG;20MG; 20MG;40MGtablet, extended release · oralPURDUE PHARMA LPDiscontinued23 Jul 2014

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
TARGIN0233960910 MG; 5 MGTABLET (EXTENDED-RELEASE) · ORALPURDUE PHARMA
TARGIN0233961720 MG; 10 MGTABLET (EXTENDED-RELEASE) · ORALPURDUE PHARMA
TARGIN0233962520 MG; 40 MGTABLET (EXTENDED-RELEASE) · ORALPURDUE PHARMA
TARGIN023874252.50 MG; 5.00 MGTABLET (EXTENDED-RELEASE) · ORALPURDUE PHARMA

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
NHS Drug TariffOxycodone 10mg / Naloxone 5mg modified-release tablets£42.3256 tablet1 Oct 2026
NHS Drug TariffOxycodone 20mg / Naloxone 10mg modified-release tablets£84.6256 tablet1 Oct 2026
NHS Drug TariffOxycodone 40mg / Naloxone 20mg modified-release tablets£169.2856 tablet1 Oct 2026
NHS Drug TariffOxycodone 5mg / Naloxone 2.5mg modified-release tablets£21.1628 tablet1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Components

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.