Is Penicillamine registered with the SFDA?

The SFDA human drug list (edition 4-2026, as published by the Council of Health Insurance) lists 1 valid registration of Penicillamine, including PenicillAMINE (250 mg, Capsule, hard, SAR 336.95).

Is Penicillamine approved by the US FDA?

Drugs@FDA lists 15 application product lines for Penicillamine, including CUPRIMINE (Prescription); DEPEN (Prescription); PENICILLAMINE (Prescription); PENICILLAMINE (Prescription); PENICILLAMINE (Prescription).

Is Penicillamine on the WHO Model List of Essential Medicines?

Yes — 4.2. Antidotes and other substances used in poisonings > Specific (core list): Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified.

Active substance

Penicillamine

SFDA 3
US FDA 15
Health Canada 1
NHS prices 2
WHO EML 2

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade name	Strength	Form · route	Pack	Public price	Type	Company	Status
PenicillAMINE	250 mg	Capsule, hard · Oral use	100 Bottle	SAR 336.95	Generic · Prescription	Navinta LLC	Valid
ARTAMIN 150 MG CAPS	150 mg	Capsule · Oral use	50 Blister	SAR 61.85	NCE · Prescription	SANDOZ	Withdrawn by MAH · Not Marketed
ARTAMIN 250 MG CAPS	250 mg	Capsule · Oral use	50 Blister	SAR 74.45	NCE · Prescription	SANDOZ	Withdrawn by MAH · Not Marketed

US FDA United States — FDA approvals (Drugs@FDA)

Product	Strength	Form · route	Applicant	Status	First approved
CUPRIMINE	250MG	capsule · oral	VALEANT PHARMS INTL	Prescription	4 Dec 1970
DEPEN	250MG	tablet · oral	MYLAN SPECIALITY LP	Prescription	8 Nov 1978
PENICILLAMINE	250MG	capsule · oral	WATSON LABS INC	Prescription	24 Jun 2019
PENICILLAMINE	250MG	tablet · oral	PH HEALTH	Prescription	23 Dec 2019
PENICILLAMINE	250MG	capsule · oral	PH HEALTH	Prescription	23 Dec 2019
PENICILLAMINE	250MG	capsule · oral	DR REDDYS	Prescription	4 Aug 2020
PENICILLAMINE	250MG	tablet · oral	LUPIN	Prescription	30 Nov 2020
PENICILLAMINE	250MG	capsule · oral	GRANULES	Prescription	2 Dec 2020
PENICILLAMINE	250MG	capsule · oral	INVAGEN PHARMS	Prescription	19 Aug 2021
PENICILLAMINE	250MG	capsule · oral	BRECKENRIDGE	Prescription	23 Aug 2021
PENICILLAMINE	250MG	capsule · oral	NAVINTA LLC	Prescription	8 Oct 2021
CUPRIMINE	125MG	capsule · oral	VALEANT PHARMS INTL	Discontinued	4 Dec 1970
LUXZYLA	250MG	capsule · oral	ANI PHARMS	Discontinued	7 May 2019
PENICILLAMINE	250MG	tablet · oral	TEVA PHARMS USA	Discontinued	13 Feb 2020
PENICILLAMINE	250MG	capsule · oral	APOTEX	Discontinued	28 Apr 2020

Canada Canada — marketed products (Health Canada)

Brand	DIN	Strength	Form · route	Company
CUPRIMINE	00016055	250 MG	CAPSULE · ORAL	BAUSCH HEALTH, CANADA INC.

Prices — United States and England

Source	Product as listed	Price	Unit / pack	Date
NHS Drug Tariff	Penicillamine 125mg tablets	£93.11	56 tablet	1 Oct 2026
NHS Drug Tariff	Penicillamine 250mg tablets	£140.00	56 tablet	1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

4.2. Antidotes and other substances used in poisonings > Specific · core
Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified
Oral > Solid: 250 mg
29.2. Disease-modifying anti-rheumatic drugs (DMARDs) · complementary
Rheumatoid arthritis, serology unspecified
Oral > Solid: 250 mg

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.