Active substance
Pentoxifylline
- SFDA 2
- US FDA 11
- Health Canada 2
- US price lines 1
- NHS prices 1
- Safety 1
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| TRENTAL TAB 400MG | 400 mg | Prolonged-release tablet · Oral use | 100 Blister | SAR 99.60 | NCE · Prescription | sanofi-aventis | Valid |
| TRENTAL TAB 400MG | 400 mg | Prolonged-release tablet · Oral use | 20 Blister | SAR 27.00 | NCE · Prescription | sanofi-aventis | Valid |
Indications — CHI Daman Drug Formulary
CHRONIC VENOUS INSUFFICIENCY; SARCOIDOSIS; VARICOSE VEINS
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| TRENTAL | 400MG | tablet, extended release · oral | VALIDUS PHARMS | Prescription | 30 Aug 1984 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | RISING | Prescription | 8 Jul 1997 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | ANI PHARMS | Prescription | 9 Jul 1997 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | APOTEX | Prescription | 9 Jun 1999 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | HERITAGE | Discontinued | 8 Jul 1997 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | BAUSCH | Discontinued | 20 Jul 1998 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | ANI PHARMS | Discontinued | 4 Sep 1998 |
| PENTOXIL | 400MG | tablet, extended release · oral | UPSHER SMITH LABS | Discontinued | 31 Mar 1999 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | PLIVA | Discontinued | 25 May 1999 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | IMPAX LABS | Discontinued | 10 Aug 1999 |
| PENTOXIFYLLINE | 400MG | tablet, extended release · oral | ANI PHARMS | Discontinued | 3 Sep 1999 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| APO-PENTOXIFYLLINE SR | 02230090 | 400 MG | TABLET (EXTENDED-RELEASE) · ORAL | APOTEX INC |
| JAMP PENTOXIFYLLINE SR | 02543087 | 400 MG | TABLET (EXTENDED-RELEASE) · ORAL | JAMP PHARMA CORPORATION |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | PENTOXIFYLLINE ER 400 MG TAB | $0.22728 | per EA | 23 Sep 2026 |
| NHS Drug Tariff | Pentoxifylline 400mg modified-release tablets | £19.39 | 90 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
Safety signals and safety-related labeling changes
- US FDA 15 Jan 2016 TRENTAL — safety-related labeling change
Labeling sections changed: Drug Interactions
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.