Regulatory PathRegulatory requirements compared

Active substance

Perphenazine

Open in the medicines table

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
PERPHENAZINE2MGtablet · oralSANDOZPrescription8 Dec 1988
PERPHENAZINE4MGtablet · oralSANDOZPrescription8 Dec 1988
PERPHENAZINE8MG; 2MG; 4MG; 16MGtablet · oralSANDOZPrescription8 Dec 1988
PERPHENAZINE16MGtablet · oralSANDOZPrescription8 Dec 1988
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralPH HEALTHPrescription31 Dec 1998
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralWILSHIRE PHARMS INCPrescription17 Dec 2015
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralWATSON LABS INCPrescription17 Oct 2016
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralRISINGPrescription1 Mar 2019
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralZYDUS PHARMSPrescription6 Apr 2020
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralSOMERSET THERAPS LLCPrescription18 May 2022
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralMACLEODS PHARMSPrescription6 May 2024
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralJUBILANT GENERICSPrescription18 Mar 2025
TRILAFON2MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 4MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 8MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 16MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralSCHERINGDiscontinued27 Feb 1957
TRILAFON5MG/MLinjectable · injectionSCHERINGDiscontinued29 Jan 1958
TRILAFON16MG/5MLconcentrate · oralSCHERINGDiscontinued12 Dec 1958
PERPHENAZINE8MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralANI PHARMSDiscontinued10 Sep 1987
PERPHENAZINE16MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralANI PHARMSDiscontinued10 Sep 1987
PERPHENAZINE2MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralANI PHARMSDiscontinued10 Sep 1987
PERPHENAZINE4MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralANI PHARMSDiscontinued10 Sep 1987
PERPHENAZINE16MG/5MLconcentrate · oralPHARM ASSOCDiscontinued25 May 2001
PERPHENAZINE2MG; 4MG; 8MG; 16MGtablet · oralMYLANDiscontinued14 Apr 2017
TRILAFON2MG/5MLsyrup · oralSCHERINGDiscontinued
TRILAFON8MGtablet, extended release · oralSCHERINGDiscontinued

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
PERPHENAZINE0033509616 MGTABLET · ORALAA PHARMA INC
PERPHENAZINE003351188 MGTABLET · ORALAA PHARMA INC
PERPHENAZINE003351264 MGTABLET · ORALAA PHARMA INC
PERPHENAZINE003351342 MGTABLET · ORALAA PHARMA INC

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACPERPHENAZINE 16 MG TABLET$0.3911per EA23 Sep 2026
US NADACPERPHENAZINE 2 MG TABLET$0.19667per EA23 Sep 2026
US NADACPERPHENAZINE 4 MG TABLET$0.16125per EA23 Sep 2026
US NADACPERPHENAZINE 8 MG TABLET$0.13539per EA23 Sep 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.