Regulatory PathRegulatory requirements compared

Active substance

Prochlorperazine

Open in the medicines table

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionHIKMA PHARMSPrescription29 Aug 1989
PROCHLORPERAZINE25MGsuppository · rectalCOSETTE PHARMS NCPrescription24 Nov 1993
PROCOMPEQ 5MG BASE; EQ 10MG BASEtablet · oralJUBILANT CADISTAPrescription27 Feb 1998
COMPRO25MGsuppository · rectalPADAGIS USPrescription28 Jun 2000
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionSAGENTPrescription28 May 2004
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionAVET LIFESCIENCESPrescription15 Oct 2013
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionMYLAN LABS LTDPrescription25 Oct 2018
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionCAPLINPrescription22 Apr 2021
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionGLANDPrescription22 Sep 2021
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionVIWIT PHARMPrescription28 Sep 2021
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralNOVITIUM PHARMAPrescription13 Jun 2022
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionEUGIA PHARMAPrescription14 Jul 2022
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralZYDUS LIFESCIENCESPrescription8 Aug 2022
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralGLENMARK PHARMS LTDPrescription17 Mar 2023
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralBIONPHARMAPrescription4 Apr 2023
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralAMNEALPrescription17 Apr 2023
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralAJANTA PHARMA LTDPrescription9 May 2024
PROCHLORPERAZINE EDISYLATEEQ 5MG BASE/MLinjectable · injectionSOMERSET THERAPS LLCPrescription13 Sep 2024
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralLEADINGPrescription30 Sep 2024
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralDR REDDYS LABS SAPrescription19 May 2025
PROCHLORPERAZINE MALEATEEQ 5MG BASE; EQ 10MG BASEtablet · oralAUROBINDO PHARMA LTDPrescription8 Sep 2025
COMPAZINEEQ 5MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; EQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; EQ 25MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralGLAXOSMITHKLINEDiscontinued23 Oct 1956
COMPAZINEEQ 5MG BASE/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**injectable · injectionGLAXOSMITHKLINEDiscontinued8 Apr 1957
COMPAZINEEQ 10MG BASE; EQ 15MG BASE; EQ 30MG BASE; EQ 75MG BASEcapsule, extended release · oralGLAXOSMITHKLINEDiscontinued5 Jun 1957
COMPAZINEEQ 5MG BASE/5MLsyrup · oralGLAXOSMITHKLINEDiscontinued10 Dec 1957

34 more — full table

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
ODAN-PROCHLORPERAZINE0078972010 MGSUPPOSITORY · RECTALODAN LABORATORIESLTD
PROCHLORAZINE0088643210 MGTABLET · ORALAA PHARMA INC
PROCHLORAZINE008864405 MGTABLET · ORALAA PHARMA INC

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACCOMPRO 25 MG SUPPOSITORY$6.74227per EA23 Sep 2026
US NADACPROCHLORPERAZINE 10 MG TAB$0.16215per EA23 Sep 2026
US NADACPROCHLORPERAZINE 25 MG SUPP$4.86511per EA23 Sep 2026
US NADACPROCHLORPERAZINE 5 MG TABLET$0.11478per EA23 Sep 2026
NHS Drug TariffProchlorperazine 12.5mg/1ml solution for injection ampoules£5.2310 ampoule1 Oct 2026
NHS Drug TariffProchlorperazine 3mg buccal tablets£16.5650 tablet1 Oct 2026
NHS Drug TariffProchlorperazine 5mg tablets£0.9328 tablet1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.