Is Sodium nitroprusside registered with the SFDA?

The SFDA human drug list (edition 4-2026, as published by the Council of Health Insurance) lists 1 valid registration of Sodium nitroprusside, including Sodium Nitroprusside (25 mg/ml, Solution for injection, SAR 230.40).

Is Sodium nitroprusside approved by the US FDA?

Drugs@FDA lists 30 application product lines for Sodium nitroprusside, including SODIUM NITROPRUSSIDE (Prescription); NIPRIDE RTU IN SODIUM CHLORIDE 0.9% (Prescription); SODIUM NITROPRUSSIDE (Prescription); SODIUM NITROPRUSSIDE (Prescription); SODIUM NITROPRUSSIDE (Prescription).

Is Sodium nitroprusside on the WHO Model List of Essential Medicines?

Yes — 12.3. Antihypertensive medicines (complementary list): Hypertensive crisis.

Active substance

Sodium nitroprusside

SFDA 3
US FDA 30
Health Canada 4
WHO EML 1

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade name	Strength	Form · route	Pack	Public price	Type	Company	Status
Sodium Nitroprusside	25 mg/ml	Solution for injection · Intravenous use	1 Vial	SAR 230.40	Generic · Prescription	Hainan Poly Pharm. Co., Ltd.	Valid
NIPRIDE DOUBLE 50 MG AMP.	50 mg	Solution · Parenteral use	5 Ampoule	SAR 131.05	NCE · Prescription	ROCHE	Withdrawn by MAH · Not Marketed
SOD.NITROPRUSSIDE 50MG VIAL	50 mg	Injection · Parenteral use	5 Vial	SAR 122.30	Generic · Prescription	HOSPIRA AUSTRALIA	Withdrawn by MAH · Not Marketed

Indications — CHI Daman Drug Formulary

HYPERTENSION

US FDA United States — FDA approvals (Drugs@FDA)

Product	Strength	Form · route	Applicant	Status	First approved
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	SAGENT PHARMS INC	Prescription	8 Dec 2016
NIPRIDE RTU IN SODIUM CHLORIDE 0.9%	50MG/100ML (0.5MG/ML); 20MG/100ML (0.2MG/ML)	solution · intravenous	EXELA PHARMA	Prescription	8 Mar 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	NEXUS	Prescription	25 May 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	AMNEAL	Prescription	7 Nov 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	MICRO LABS	Prescription	8 Dec 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	MYLAN LABS LTD	Prescription	17 Apr 2018
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	SOMERSET THERAPS LLC	Prescription	17 Aug 2018
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	DR REDDYS	Prescription	10 Apr 2019
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	CAPLIN	Prescription	29 Nov 2019
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	HAINAN POLY	Prescription	25 Aug 2020
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	BE PHARMS	Prescription	12 Jul 2021
SODIUM NITROPRUSSIDE	10MG/50ML (0.2MG/ML); 20MG/100ML (0.2MG/ML); 50MG/100ML (0.5MG/ML)	solution · intravenous	HAINAN POLY	Prescription	26 Aug 2022
NIPRIDE	50MG/VIAL	injectable · injection	ROCHE	Discontinued	10 May 1974
NITROPRESS	50MG/VIAL Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	injectable · injection	ABBVIE	Discontinued	8 Sep 1981
SODIUM NITROPRUSSIDE	50MG/VIAL Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	injectable · injection	BAXTER HLTHCARE	Discontinued	28 Jul 1982
NITROPRESS	50MG/VIAL	injectable · injection	HOSPIRA	Discontinued	9 Jun 1986
NITROPRESS	50MG/VIAL	injectable · injection	ABBOTT	Discontinued	16 Nov 1987
NITROPRESS	25MG/ML	injectable · injection	VPNA	Discontinued	1 Aug 1988
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	TEVA PARENTERAL	Discontinued	30 Mar 1992
NIPRIDE RTU IN SODIUM CHLORIDE 0.9%	10MG/50ML (0.2MG/ML) Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	solution · intravenous	EXELA PHARMA	Discontinued	8 Mar 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	EPIC PHARMA LLC	Discontinued	4 May 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	AMPHASTAR PHARMS INC	Discontinued	18 Dec 2017
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	CHARTWELL RX	Discontinued	26 Jun 2018
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	CIPLA	Discontinued	16 Jul 2018
SODIUM NITROPRUSSIDE	25MG/ML	injectable · injection	PHARMOBEDIENT	Discontinued	10 Aug 2018

5 more — full table

Canada Canada — marketed products (Health Canada)

Brand	DIN	Strength	Form · route	Company
SODIUM NITROPRUSSIDE FOR INJECTION	02450089	25 MG / ML	SOLUTION · INTRAVENOUS	STERIMAX INC
SODIUM NITROPRUSSIDE FOR INJECTION	02479109	25 MG / ML	SOLUTION · INTRAVENOUS	MARCAN PHARMACEUTICALS INC
SODIUM NITROPRUSSIDE FOR INJECTION	02507404	25 MG / ML	SOLUTION · INTRAVENOUS	DR REDDY'S LABORATORIES LTD
SODIUM NITROPRUSSIDE FOR INJECTION	02542129	25 MG / ML	SOLUTION · INTRAVENOUS	JAMP PHARMA CORPORATION

WHO WHO Model List of Essential Medicines (2025)

12.3. Antihypertensive medicines · complementary
Hypertensive crisis
Parenteral > General injections > IV: 50 mg in ampoule powder for infusion

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.