Active substance
Timolol
- SFDA 20
- US FDA 64
- Health Canada 10
- US price lines 18
- NHS prices 8
- WHO EML 1
- Safety 7
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| APIMOL 0.25% EYE DROPS | 0.25 % | Eye drops · Ophthalmic use | 1 Dropper Container | SAR 9.15 | Generic · Prescription | Amman Pharmaceutical Industries (API) | Valid |
| APIMOL 0.5% EYE DROPS | 0.5 % | Eye drops · Ophthalmic use | 1 Dropper Container | SAR 9.95 | Generic · Prescription | Amman Pharmaceutical Industries (API) | Valid |
| OCUMOL 0.5% | 0.5 % | Eye drops · Ophthalmic use | 1 Dropper Container | SAR 24.40 | Generic · Prescription | RIYADH PHARMA | Valid |
| OPTIMOL 0.5% OPHTHALMIC SOLUTION | 0.5 % | Eye drops, solution · Ophthalmic use | 1 Dropper Container | SAR 31.50 | Generic · Prescription | Jamjoom Pharmaceuticals Factory Company | Valid |
| TIMOLOL 0.5% OPHTHALMIC SOLUTION | 0.5 % | Ophthalmic solution · Ophthalmic use | 20 Dropper Container | SAR 35.15 | Generic · Prescription | Pharmaceutical Solution Industries (PSI) | Valid |
| TIMOPTOL .DROPS | 0.25 % | Eye drops, solution · Ocular use | 1 Dropper Container | SAR 27.25 | NCE · Prescription | MUNDIPHARMA PTY LTD | Valid |
| TIMOPTOL .DROPS | 0.5 % | Eye drops, solution · Ocular use | 1 Dropper Container | SAR 33.10 | NCE · Prescription | MUNDIPHARMA PTY LTD | Valid |
| CUSIMOLOL 0.25% EYE DROPS | 0.25 % | Eye drops · Ocular use | 1 Dropper Container | SAR 12.75 | Generic · Prescription | ALCON CUSI | Withdrawn by MAH · Not Marketed |
| CUSIMOLOL 0.5% EYE DROPS | 0.5 % | Eye drops · Ocular use | 1 Dropper Container | SAR 13.65 | Generic · Prescription | ALCON CUSI | Withdrawn by MAH · Not Marketed |
| NYOLOL 0.1% OPHTHALMIC GEL | 0.1 % | eye gel · Ocular use | 1 Tube | SAR 23.00 | Generic · Prescription | NOVARTIS | Withdrawn by MAH · Not Marketed |
| NYOLOL 0.25% EYE DROP | 0.25 % | Eye drops · Ophthalmic use | 1 Dropper Container | SAR 10.50 | Generic · Prescription | Excel Vision | Invalid · Not Marketed |
| NYOLOL 0.5% EYE DROP | 0.5 % | Eye drops · Ocular use | 1 Dropper Container | SAR 11.00 | Generic · Prescription | NOVARTIS | Withdrawn by MAH · Not Marketed |
| OCUMOL | 0.25 % | Eye drops · Ophthalmic use | 1 Dropper Container | SAR 20.50 | Generic · Prescription | RIYADH PHARMA | Withdrawn by MAH · Not Marketed |
| OFTAN TIMOLOL 0.25% EYE DROPS | 0.25 % | Eye drops · Ocular use | 60 Dropper Container | SAR 38.45 | Generic · Prescription | BAYER SCHERING PHARMA | Withdrawn by MAH · Not Marketed |
| OFTAN TIMOLOL 0.25% EYE DROPS | 0.25 % | Eye drops · Ocular use | 1 Dropper Container | SAR 13.00 | Generic · Prescription | BAYER SCHERING PHARMA | Withdrawn by MAH · Not Marketed |
| OFTAN TIMOLOL 0.5% EYE DROPS | 0.5 % | Eye drops · Ocular use | 1 Dropper Container | SAR 14.15 | Generic · Prescription | BAYER SCHERING PHARMA | Withdrawn by MAH · Not Marketed |
| OFTAN TIMOLOL 0.5% EYE DROPS | 0.5 % | Eye drops · Ocular use | 60 Dropper Container | SAR 39.25 | Generic · Prescription | BAYER SCHERING PHARMA | Withdrawn by MAH · Not Marketed |
| OPHTAMOLOL 0.25% EYE DROPS | 0.25 % | Eye drops · Ocular use | 1 Dropper Container | SAR 11.30 | Generic · Prescription | DAR ALDAWA | Withdrawn by MAH · Not Marketed |
| OPHTAMOLOL 0.5% EYE DROPS | 0.5 % | Eye drops · Ocular use | 1 Dropper Container | SAR 12.35 | Generic · Prescription | DAR ALDAWA | Withdrawn by MAH · Not Marketed |
| OPTIMOL 0.25% OPHTHALMIC SOLUTION | 0.25 % | Eye drops, solution · Ophthalmic use | 1 Dropper Container | SAR 25.80 | Generic · Prescription | Jamjoom Pharmaceuticals Factory Company | Withdrawn by MAH · Not Marketed |
Indications — CHI Daman Drug Formulary
INFANTILE HEMANGIOMA; NON-INFECTIOUS UVEITIS; OPEN ANGLE GLUCOMA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| TIMOPTIC | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | BAUSCH AND LOMB INC | Prescription | 17 Aug 1978 |
| TIMOPTIC IN OCUDOSE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | BAUSCH AND LOMB INC | Prescription | 5 Nov 1986 |
| TIMOLOL MALEATE | 10MG | tablet · oral | MYLAN | Prescription | 8 Jun 1990 |
| TIMOPTIC-XE | EQ 0.25% BASE; EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | BAUSCH AND LOMB INC | Prescription | 4 Nov 1993 |
| BETIMOL | 0.5% | solution/drops · ophthalmic | THEA PHARMA | Prescription | 31 Mar 1995 |
| TIMOLOL MALEATE | EQ 0.25% BASE | solution/drops · ophthalmic | SANDOZ | Prescription | 28 Apr 1995 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | SANDOZ | Prescription | 28 Apr 1995 |
| TIMOLOL MALEATE | EQ 0.25% BASE | solution/drops · ophthalmic | ABBVIE | Prescription | 25 Mar 1997 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | ABBVIE | Prescription | 25 Mar 1997 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | SANDOZ | Prescription | 21 Oct 1998 |
| ISTALOL | EQ 0.5% BASE | solution/drops · ophthalmic | BAUSCH AND LOMB | Prescription | 4 Jun 2004 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | FDC LTD | Prescription | 30 Apr 2008 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | MANKIND PHARMA | Prescription | 28 Sep 2009 |
| TIMOLOL MALEATE | 5MG; 10MG; 20MG | tablet · oral | RISING | Prescription | 2 May 2019 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | EPIC PHARMA LLC | Prescription | 11 Sep 2020 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | ALEMBIC | Prescription | 22 Oct 2020 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | J MOLNER | Prescription | 13 Dec 2021 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | GLAND | Prescription | 24 Jun 2022 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | MICRO LABS | Prescription | 7 Sep 2022 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | INGENUS PHARMS LLC | Prescription | 13 Sep 2022 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | DR REDDYS | Prescription | 22 Sep 2022 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution, gel forming/drops · ophthalmic | EUGIA PHARMA | Prescription | 23 Mar 2023 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | SENTISS PHARMA | Prescription | 8 May 2023 |
| TIMOLOL MALEATE | EQ 0.25% BASE; EQ 0.5% BASE | solution/drops · ophthalmic | MICRO LABS | Prescription | 26 May 2023 |
| TIMOLOL MALEATE | EQ 0.5% BASE | solution/drops · ophthalmic | SOMERSET THERAPS LLC | Prescription | 3 Jul 2024 |
39 more — full table
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| JAMP-TIMOLOL | 02447800 | 0.5 % | SOLUTION · OPHTHALMIC | JAMP PHARMA CORPORATION |
| SANDOZ TIMOLOL | 02166712 | 0.25 % | SOLUTION · OPHTHALMIC | SANDOZ CANADA INCORPORATED |
| SANDOZ TIMOLOL | 02166720 | 0.5 % | SOLUTION · OPHTHALMIC | SANDOZ CANADA INCORPORATED |
| TIMOLOL | 00755842 | 5 MG | TABLET · ORAL | AA PHARMA INC |
| TIMOLOL | 00755850 | 10 MG | TABLET · ORAL | AA PHARMA INC |
| TIMOLOL | 00755869 | 20 MG | TABLET · ORAL | AA PHARMA INC |
| TIMOLOL MALEATE-EX | 02242275 | 0.25 % | SOLUTION (EXTENDED-RELEASE) · OPHTHALMIC | SANDOZ CANADA INCORPORATED |
| TIMOLOL MALEATE-EX | 02242276 | 0.5 % | SOLUTION (EXTENDED-RELEASE) · OPHTHALMIC | SANDOZ CANADA INCORPORATED |
| TIMOPTIC | 00451207 | 0.5 % | SOLUTION · OPHTHALMIC | ELVIUM LIFE SCIENCES |
| TIMOPTIC-XE | 02171899 | 0.5 % | SOLUTION (EXTENDED-RELEASE) · OPHTHALMIC | ELVIUM LIFE SCIENCES |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | BETIMOL 0.5% EYE DROPS | $31.12233 | per ML | 18 Feb 2026 |
| US NADAC | ISTALOL 0.5% EYE DROPS | $79.76333 | per ML | 17 Jun 2026 |
| US NADAC | ISTALOL 0.5% EYE DROPS | $80.01457 | per ML | 22 Jul 2026 |
| US NADAC | TIMOLOL 0.25% GEL-SOLUTION | $6.37609 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL 0.5% EYE DROP | $21.80573 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL 0.5% EYE DROP | $22.28973 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL 0.5% EYE DROPS | $21.6742 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL 0.5% GEL-SOLUTION | $8.30197 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL 0.5% GFS GEL-SOLUTION | $8.30197 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL MALEATE 0.25% EYE DROP | $6.10159 | per EA | 23 Sep 2026 |
| US NADAC | TIMOLOL MALEATE 0.25% EYE DROP | $0.64351 | per ML | 23 Sep 2026 |
| US NADAC | TIMOLOL MALEATE 0.25% EYE DROP | $0.64657 | per ML | 23 Sep 2026 |
| NHS Drug Tariff | Timolol 0.25% eye drops | £4.64 | 5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 0.25% eye gel | £3.12 | 2.5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 0.5% eye drops | £4.24 | 5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 0.5% eye gel | £3.12 | 2.5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 10mg tablets | £93.24 | 30 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 1mg/g gel eye drops 0.4g unit dose preservative free | £7.49 | 30 unit dose | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 2.5mg/ml eye drops preservative free | £8.45 | 5 ml | 1 Oct 2026 |
| NHS Drug Tariff | Timolol 5mg/ml eye drops preservative free | £9.65 | 5 ml | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 21.4. Ophthalmological preparations > Miotics and antiglaucoma medicines · core
Ocular hypertension; Primary open-angle glaucoma
Local > Ophthalmological > Solution (eye drops): 0.25% (hydrogen maleate); 0.5% (hydrogen maleate)
Safety signals and safety-related labeling changes
- US FDA 9 Apr 2026 COSOPT PF — safety-related labeling change
Labeling sections changed: Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 17 Mar 2026 COMBIGAN — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Adverse Reactions; Use in Specific Populations - US FDA 28 May 2024 TIMOLOL MALEATE — safety-related labeling change
Labeling sections changed: Warnings and Precautions; Drug Interactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - US FDA 23 Nov 2020 COSOPT — safety-related labeling change
Labeling sections changed: Patient Counseling Information / Patient Information / Medication Guide - US FDA 16 Jul 2018 TIMOPTIC-XE — safety-related labeling change
Labeling sections changed: Use in Specific Populations - US FDA 6 Apr 2017 TIMOPTIC IN OCUDOSE — safety-related labeling change
Labeling sections changed: Use in Specific Populations - US FDA 9 Aug 2016 TIMOPTIC — safety-related labeling change
Labeling sections changed: Use in Specific Populations
Combinations containing Timolol
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.