Regulatory PathRegulatory requirements compared

Active substance

Trifarotene

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade nameStrengthForm · routePackPublic priceTypeCompanyStatus
AKLIEF50 µg/gCream · Topical1 TubeSAR 139.80NCE · PrescriptionGALDERMAValid

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
AKLIEF0.005%cream · topicalGALDERMA LABS LPPrescription4 Oct 2019

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
AKLIEF0249417550 MCG / GCREAM · TOPICALGALDERMA CANADA INC.

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACAKLIEF 0.005% CREAM$16.36232per GM23 Sep 2026
NHS Drug TariffTrifarotene 50micrograms/g cream£27.7575 gram1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.