Regulatory PathRegulatory requirements compared

Active substance

Trihexyphenidyl

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade nameStrengthForm · routePackPublic priceTypeCompanyStatus
ARTANE 2 MG TAB2 mgTablet · Oral use100 Tablet ContainerSAR 16.80NCE · PrescriptionWYETHWithdrawn by MAH · Not Marketed
ARTANE 5 MG TAB5 mgTablet · Oral use100 Tablet ContainerSAR 22.20NCE · PrescriptionWYETHWithdrawn by MAH · Not Marketed

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
TRIHEXYPHENIDYL HYDROCHLORIDE2MGtablet · oralWATSON LABSPrescription26 Nov 1974
TRIHEXYPHENIDYL HYDROCHLORIDE5MGtablet · oralWATSON LABSPrescription6 Dec 1974
TRIHEXYPHENIDYL HYDROCHLORIDE2MG/5MLelixir · oralPHARM ASSOCPrescription17 Apr 1997
TRIHEXYPHENIDYL HYDROCHLORIDE2MG; 5MGtablet · oralNOVITIUM PHARMAPrescription24 Dec 1998
TRIHEXYPHENIDYL HYDROCHLORIDE2MG/5MLelixir · oralCHARTWELL RXPrescription27 Sep 1999
TRIHEXYPHENIDYL HYDROCHLORIDE2MG; 5MGtablet · oralNATCO PHARMA LTDPrescription17 Nov 2010
ARTANE5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**; 2MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**tablet · oralLEDERLEDiscontinued13 May 1949
ARTANE2MG/5MLelixir · oralLEDERLEDiscontinued13 May 1949
ARTANE5MGcapsule, extended release · oralLEDERLEDiscontinued13 May 1949
ARTANE5MGcapsule, extended release · oralLEDERLEDiscontinued18 Apr 1962
TRIHEXYPHENIDYL HYDROCHLORIDE2MGtablet · oralVANGARDDiscontinued30 Jul 1982
TRIHEXYPHENIDYL HYDROCHLORIDE2MG/5MLelixir · oralPHARM VENTURESDiscontinued7 Apr 1989
TRIHEXYPHENIDYL HYDROCHLORIDE2MG; 5MGtablet · oralWATSON LABSDiscontinued6 Feb 1998
TRIHEXYPHENIDYL HYDROCHLORIDE5MG; 2MGtablet · oralHIKMADiscontinued16 Feb 2000
TREMIN2MG; 5MGtablet · oralSCHERINGDiscontinued
TRIHEXYPHENIDYL HYDROCHLORIDE5MGtablet · oralWATSON LABSDiscontinued
TRIHEXYPHENIDYL HYDROCHLORIDE2MGtablet · oralWATSON LABSDiscontinued
TRIHEXYPHENIDYL HYDROCHLORIDE5MGtablet · oralNYLOSDiscontinued

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
TRIHEXYPHENIDYL005450582 MGTABLET · ORALAA PHARMA INC
TRIHEXYPHENIDYL005450745 MGTABLET · ORALAA PHARMA INC

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACTRIHEXYPHENIDYL 2 MG TABLET$0.08838per EA23 Sep 2026
US NADACTRIHEXYPHENIDYL 5 MG TABLET$0.1191per EA23 Sep 2026
NHS Drug TariffTrihexyphenidyl 2mg tablets£142.4384 tablet1 Oct 2026
NHS Drug TariffTrihexyphenidyl 5mg tablets£214.9484 tablet1 Oct 2026
NHS Drug TariffTrihexyphenidyl 5mg/5ml oral solution£118.41200 ml1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

  • 5.1.3. Medicines for parkinsonism · core
    Therapeutic equivalent to biperiden for Parkinson disease

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.