Active substance
Valaciclovir
- SFDA 4
- US FDA 18
- Health Canada 22
- US price lines 4
- NHS prices 4
- WHO EML 1
- Safety 3
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| Herptrex | 500 mg | Film-coated tablet · Oral use | 60 Blister | SAR 381.00 | Generic · Prescription | Saudi Amarox | Valid |
| Herptrex | 500 mg | Film-coated tablet · Oral use | 10 Blister | SAR 73.40 | Generic · Prescription | Saudi Amarox | Valid |
| VALTREX | 500 mg | Tablet · Oral use | 42 Blister | SAR 319.80 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
| VALTREX | 500 mg | Tablet · Oral use | 10 Blister | SAR 86.35 | NCE · Prescription | GLAXO SAUDI ARABIA | Valid |
Indications — CHI Daman Drug Formulary
ANTIMICROBIAL PROPHYLAXIS IN CANCER PATIENTS; BELL'S PALSY; CHICKENPOX (VARICELLA); HERPES SIMPLEX VIRUS (HERPES LABIALIS); HERPES ZOSTER (SHINGLES); HERPESVIRAL KERATITIS, ZOSTER KERATITIS, KERATITIS, VARICELLA KERATITIS; INFECTIOUS UVEITIS; MULTIPLE MYELOMA
US FDA United States — FDA approvals (Drugs@FDA)
| Product | Strength | Form · route | Applicant | Status | First approved |
|---|---|---|---|---|---|
| VALTREX | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | GLAXOSMITHKLINE | Prescription | 23 Jun 1995 |
| VALTREX | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | GLAXOSMITHKLINE | Prescription | 15 Dec 1995 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | SUN PHARM INDS LTD | Prescription | 31 Jan 2007 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | MYLAN PHARMS INC | Prescription | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | RISING | Prescription | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | CHARTWELL RX | Prescription | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | AUROBINDO PHARMA | Prescription | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | JUBILANT GENERICS | Prescription | 3 Apr 2012 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | HETERO LABS LTD V | Prescription | 8 Apr 2015 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | ZYDUS LIFESCIENCES | Prescription | 29 Dec 2017 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | YILING | Prescription | 18 Mar 2020 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | CIPLA | Discontinued | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | AIPING PHARM INC | Discontinued | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | TEVA PHARMS | Discontinued | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | PHARMOBEDIENT | Discontinued | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | HIKMA PHARMS | Discontinued | 24 May 2010 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | WATSON LABS INC | Discontinued | 16 Mar 2011 |
| VALACYCLOVIR HYDROCHLORIDE | EQ 500MG BASE; EQ 1GM BASE | tablet · oral | APOTEX | Discontinued | 4 Apr 2014 |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| AG-VALACYCLOVIR | 02500582 | 500 MG | TABLET · ORAL | ANGITA PHARMA INC. |
| APO-VALACYCLOVIR | 02295822 | 500 MG | TABLET · ORAL | APOTEX INC |
| APO-VALACYCLOVIR | 02354705 | 1000 MG | TABLET · ORAL | APOTEX INC |
| AURO-VALACYCLOVIR | 02405040 | 500 MG | TABLET · ORAL | AURO PHARMA INC |
| AURO-VALACYCLOVIR | 02405059 | 1000 MG | TABLET · ORAL | AURO PHARMA INC |
| JAMP VALACYCLOVIR | 02440598 | 500 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| JAMP VALACYCLOVIR | 02558858 | 1000 MG | TABLET · ORAL | JAMP PHARMA CORPORATION |
| MYLAN-VALACYCLOVIR | 02351560 | 1000 MG | TABLET · ORAL | MYLAN PHARMACEUTICALS ULC |
| MYLAN-VALACYCLOVIR | 02351579 | 500 MG | TABLET · ORAL | MYLAN PHARMACEUTICALS ULC |
| NB-VALACYCLOVIR | 02558130 | 500 MG | TABLET · ORAL | NB PHARMA INC. |
| PMS-VALACYCLOVIR | 02298457 | 500 MG | TABLET · ORAL | PHARMASCIENCE INC |
| PMS-VALACYCLOVIR | 02381230 | 1000 MG | TABLET · ORAL | PHARMASCIENCE INC |
| PRO-VALACYCLOVIR | 02315173 | 500 MG | TABLET · ORAL | PRO DOC LIMITEE |
| RIVA-VALACYCLOVIR | 02316447 | 500 MG | TABLET · ORAL | LABORATOIRE RIVA INC. |
| SANDOZ VALACYCLOVIR | 02347091 | 500 MG | TABLET · ORAL | SANDOZ CANADA INCORPORATED |
| TEVA-VALACYCLOVIR | 02357534 | 500 MG | TABLET · ORAL | TEVA CANADA LIMITED |
| VALACYCLOVIR | 02442000 | 500 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| VALACYCLOVIR | 02454645 | 500 MG | TABLET · ORAL | SANIS HEALTH INC |
| VALACYCLOVIR | 02519585 | 1000 MG | TABLET · ORAL | SANIS HEALTH INC |
| VALACYCLOVIR | 02553511 | 1000 MG | TABLET · ORAL | SIVEM PHARMACEUTICALS ULC |
| VALTREX | 02219492 | 500 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
| VALTREX | 02246559 | 1000 MG | TABLET · ORAL | GLAXOSMITHKLINE INC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| US NADAC | VALACYCLOVIR HCL 1 GRAM TABLET | $0.41001 | per EA | 23 Sep 2026 |
| US NADAC | VALACYCLOVIR HCL 500 MG TABLET | $0.22889 | per EA | 23 Sep 2026 |
| US NADAC | VALTREX 1 GRAM CAPLET | $20.244 | per EA | 20 May 2026 |
| US NADAC | VALTREX 500 MG CAPLET | $12.80513 | per EA | 20 May 2026 |
| NHS Drug Tariff | Valaciclovir 1g tablets | £33.98 | 10 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Valaciclovir 1g tablets | £73.47 | 21 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Valaciclovir 250mg tablets | £123.28 | 60 tablet | 1 Oct 2026 |
| NHS Drug Tariff | Valaciclovir 500mg tablets | £8.35 | 10 tablet | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 5.1.6.2. Medicines for viral central nervous system infections · core
Therapeutic equivalent to aciclovir for Zoster; Therapeutic equivalent to aciclovir for Herpes simplex infections; Therapeutic equivalent to aciclovir for Varicella
Safety signals and safety-related labeling changes
- US FDA 12 Nov 2025 VALTREX — safety-related labeling change
Labeling sections changed: Contraindications; Warnings and Precautions; Adverse Reactions; Use in Specific Populations; Patient Counseling Information / Patient Information / Medication Guide - EMA PRAC 13 Jun 2024 PRAC signal: Acute hepatitis
Action for MAH: update of the product information: No - EMA PRAC 8 Feb 2024 PRAC signal: Acute hepatitis
Action for MAH: update of the product information: No
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.