Regulatory PathRegulatory requirements compared

Active substance

Verapamil

Open in the medicines table

SFDA Saudi Arabia — SFDA human drug list

Trade nameStrengthForm · routePackPublic priceTypeCompanyStatus
ISOPTIN AMP 2.5MG-ML2.5 mg/mlSolution for injection · Intravenous use5 AmpouleSAR 14.20NCE · PrescriptionAbbott LaboratoriesValid
ISOPTIN RETARD TAB 120MG120 mgProlonged-release tablet · Oral use20 BlisterSAR 20.15NCE · PrescriptionAbbott LaboratoriesValid
ISOPTIN S.R 240MG F.COATED TAB240 mgProlonged-release tablet · Oral use20 BlisterSAR 41.95Generic · PrescriptionAbbott LaboratoriesValid
ISOPTIN TABLETS 40 MG.40 mgTablet · Oral use50 BlisterSAR 18.10NCE · PrescriptionAbbott LaboratoriesValid
ISOPTIN TABLETS 80 MG.80 mgTablet · Oral use20 BlisterSAR 14.70NCE · PrescriptionAbbott LaboratoriesValid
ISOVERA2.5 mg/mlSolution for injection · Intravenous use5 VialSAR 14.20Generic · PrescriptionSaudi AmaroxValid
Verapamil QO2.5 mgSolution for injection · Intravenous use5 VialSAR 14.20Generic · PrescriptionQomel CoValid
Indications — CHI Daman Drug Formulary

ANESTHESIA-SUPPORTIVE AGENTS/ CARDIAC ARREST, CARDIOVASCULAR EMERGENCIES AND/OR DYSRHYTHMIAS; ARRHYTHMIA; ATRIAL FIBRILLATION; BURN MANAGEMENT; CARDIOMYOPATHY; HYPERTENSION; SUPRAVENTRICULAR TACHYCARDIA; VENTRICULAR TACHYCARDIA

US FDA United States — FDA approvals (Drugs@FDA)

ProductStrengthForm · routeApplicantStatusFirst approved
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML)solution · intravenousEXELA PHARMAPrescription30 Mar 1984
VERAPAMIL HYDROCHLORIDE120MGtablet · oralWATSON LABSPrescription1 Oct 1986
VERAPAMIL HYDROCHLORIDE80MGtablet · oralWATSON LABSPrescription1 Oct 1986
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML); 10MG/4ML (2.5MG/ML)solution · intravenousHOSPIRAPrescription6 May 1987
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML)solution · intravenousHOSPIRAPrescription6 May 1987
VERAPAMIL HYDROCHLORIDE120MG; 40MG; 80MGtablet · oralHERITAGEPrescription5 Apr 1988
VERELAN120MG; 240MG; 180MG; 360MGcapsule, extended release · oralAZURITYPrescription29 May 1990
VERAPAMIL HYDROCHLORIDE40MGtablet · oralWATSON LABSPrescription29 Jun 1993
VERELAN PM100MG; 200MG; 300MGcapsule, extended release · oralAZURITYPrescription25 Nov 1998
VERAPAMIL HYDROCHLORIDE120MG; 180MG; 240MGcapsule, extended release · oralMYLANPrescription20 Apr 1999
VERAPAMIL HYDROCHLORIDE120MG; 240MGtablet, extended release · oralSTRIDES PHARMA INTLPrescription25 May 1999
VERAPAMIL HYDROCHLORIDE240MGtablet, extended release · oralGLENMARK PHARMS LTDPrescription17 Sep 2009
VERAPAMIL HYDROCHLORIDE120MG; 180MGtablet, extended release · oralGLENMARK PHARMS LTDPrescription3 Aug 2011
VERAPAMIL HYDROCHLORIDE180MG; 240MG; 120MGtablet, extended release · oralCADILA PHARMS LTDPrescription5 May 2017
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML); 10MG/4ML (2.5MG/ML)solution · intravenousSOMERSET THERAPS LLCPrescription18 Jun 2018
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML); 10MG/4ML (2.5MG/ML)solution · intravenousSOMERSETPrescription18 Jun 2018
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML); 10MG/4ML (2.5MG/ML)solution · intravenousMICRO LABSPrescription28 Dec 2018
VERAPAMIL HYDROCHLORIDE10MG/4ML (2.5MG/ML); 5MG/2ML (2.5MG/ML)solution · intravenousNEPHRONPrescription17 Mar 2020
VERAPAMIL HYDROCHLORIDE5MG/2ML (2.5MG/ML); 10MG/4ML (2.5MG/ML)solution · intravenousCAPLINPrescription25 Mar 2020
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionEUGIA PHARMAPrescription6 Jul 2020
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionZYDUS PHARMSPrescription15 Oct 2020
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionGLANDPrescription15 Oct 2020
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionHERITAGEPrescription17 Mar 2022
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionMANKIND PHARMAPrescription15 Jun 2022
VERAPAMIL HYDROCHLORIDE2.5MG/MLinjectable · injectionFRESENIUS KABI USAPrescription23 Apr 2024

53 more — full table

Canada Canada — marketed products (Health Canada)

BrandDINStrengthForm · routeCompany
AA-VERAP0078248380 MGTABLET · ORALAA PHARMA INC
AA-VERAP00782491120 MGTABLET · ORALAA PHARMA INC
ISOPTIN SR01907123120 MGTABLET (EXTENDED-RELEASE) · ORALBGP PHARMA ULC
MYLAN-VERAPAMIL SR02210347120 MGTABLET (EXTENDED-RELEASE) · ORALMYLAN PHARMACEUTICALS ULC
VERAPAMIL HYDROCHLORIDE INJECTION USP021667392.5 MG / MLLIQUID · INTRAVENOUSSANDOZ CANADA INCORPORATED

Prices — United States and England

SourceProduct as listedPriceUnit / packDate
US NADACVERAPAMIL 120 MG TABLET$0.08873per EA23 Sep 2026
US NADACVERAPAMIL 40 MG TABLET$0.11259per EA23 Sep 2026
US NADACVERAPAMIL 80 MG TABLET$0.07325per EA23 Sep 2026
US NADACVERAPAMIL ER 120 MG CAPSULE$2.74927per EA23 Sep 2026
US NADACVERAPAMIL ER 120 MG TABLET$0.17779per EA23 Sep 2026
US NADACVERAPAMIL ER 180 MG CAPSULE$2.08661per EA23 Sep 2026
US NADACVERAPAMIL ER 180 MG TABLET$0.19107per EA23 Sep 2026
US NADACVERAPAMIL ER 240 MG CAPSULE$3.1476per EA23 Sep 2026
US NADACVERAPAMIL ER 240 MG TABLET$0.17613per EA23 Sep 2026
US NADACVERAPAMIL SR 120 MG CAPSULE$2.74927per EA23 Sep 2026
US NADACVERAPAMIL SR 180 MG CAPSULE$2.08661per EA23 Sep 2026
US NADACVERAPAMIL SR 240 MG CAPSULE$3.1476per EA23 Sep 2026
NHS Drug TariffVerapamil 120mg modified-release tablets£9.5028 tablet1 Oct 2026
NHS Drug TariffVerapamil 120mg tablets£4.1428 tablet1 Oct 2026
NHS Drug TariffVerapamil 160mg tablets£31.5356 tablet1 Oct 2026
NHS Drug TariffVerapamil 240mg modified-release tablets£5.5528 tablet1 Oct 2026
NHS Drug TariffVerapamil 40mg tablets£1.8684 tablet1 Oct 2026
NHS Drug TariffVerapamil 40mg/5ml oral solution sugar free£158.85150 ml1 Oct 2026
NHS Drug TariffVerapamil 5mg/2ml solution for injection ampoules£5.415 ampoule1 Oct 2026
NHS Drug TariffVerapamil 80mg tablets£2.5184 tablet1 Oct 2026

NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.

WHO WHO Model List of Essential Medicines (2025)

  • 12.1. Antianginal medicines · core
    Angina pectoris
    Oral > Solid: 40 mg (hydrochloride); 80 mg (hydrochloride)
  • 5.1.5.3. Medicines for cluster headache · core
    Trigeminal autonomic cephalalgias
    Oral > Solid > tablet: 120 mg (hydrochloride) (immediate-release); 40 mg (hydrochloride) (immediate-release); 80 mg (hydrochloride) (immediate-release); 120 mg (hydrochloride) (extended-release); 180 mg (hydrochloride) (extended-release); 240 mg (hydrochloride) (extended-release)
  • 12.2. Antiarrhythmic medicines · core
    Supraventricular tachyarrhythmia
    Parenteral > General injections > IV: 2.5 mg per mL in 2 mL ampoule (hydrochloride) | Oral > Solid: 40 mg (hydrochloride); 80 mg (hydrochloride)

Safety signals and safety-related labeling changes

All safety entries for verapamil →

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.