Active substance
Xylometazoline
- SFDA 21
- Health Canada 5
- NHS prices 3
- WHO EML 1
- Safety 2
SFDA Saudi Arabia — SFDA human drug list
| Trade name | Strength | Form · route | Pack | Public price | Type | Company | Status |
|---|---|---|---|---|---|---|---|
| DECOZAL 0.05% METERED DOSE NASAL SPRAY | 0.05 % | Nasal spray · Nasal use | 1 Spray Container | SAR 5.50 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| DECOZAL 0.05% NASAL DROPS | 0.05 % | Nasal drops · Nasal use | 1 Dropper Container | SAR 5.50 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| DECOZAL 0.1% NASAL DROPS | 0.1 % | Nasal drops · Nasal use | 1 Dropper Container | SAR 5.60 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| DECOZAL NASAL SPRAY | 0.1 % | Spray · Nasal use | 1 Nasal Applicator | SAR 7.55 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| Decozal | 0.05 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 8.25 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| Decozal menthol | 0.1 % | Nasal spray, solution · Nasal use | 1 Bottle | SAR 13.10 | Generic · OTC | Amman Pharmaceutical Industries (API) | Valid |
| OTRIVIN DOSING SPRAY 0.1% | 0.1 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 16.55 | NCE · OTC | Haleon Schweiz AG | Valid |
| OTRIVIN NASAL DROPS 0.05% | 0.05 % | Nasal drops, solution · Nasal use | 1 Dropper Container | SAR 10.10 | NCE · OTC | Haleon Schweiz AG | Valid |
| OTRIVIN NASAL DROPS 0.1% | 0.1 % | Nasal drops, solution · Nasal use | 1 Dropper Container | SAR 11.05 | NCE · OTC | Haleon Schweiz AG | Valid |
| XYLO-MEPHA 0.1% NASAL SPRAY | 0.1 % | Nasal spray · Nasal use | 1 Spray Container | SAR 9.65 | Generic · OTC | ACINO PHARMA AG | Valid |
| XYLOLIN 0.05%CHILD NASAL SPRAY | 0.05 % | Nasal spray · Nasal use | 1 Spray Container | SAR 5.25 | Generic · OTC | Gulf Pharmaceutical Industries (Julphar) | Valid |
| XYLOLIN 0.1% ADULT NASAL SPRAY | 0.1 % | Nasal spray · Nasal use | 1 Spray Container | SAR 9.20 | Generic · OTC | Gulf Pharmaceutical Industries (Julphar) | Valid |
| XYLOMET Adult nasal drops | 0.1 % | Nasal drops · Nasal use | 1 Bottle | SAR 9.00 | Generic · OTC | RIYADH PHARMA | Valid |
| XYLOMET Peadiatric nasal drops | 0.05 % | Nasal drops · Nasal use | 1 Bottle | SAR 9.00 | Generic · OTC | RIYADH PHARMA | Valid |
| NAZIX NASAL DROPS 0.05% W-V | 0.05 % | Nasal drops, solution · Nasal use | 1 Dropper Container | SAR 4.65 | Generic · OTC | SPIMACO ADDWAEIH | Withdrawn by MAH · Not Marketed |
| NAZIX NASAL DROPS 0.1% W-V | 0.1 % | Nasal drops, solution · Nasal use | 1 Dropper Container | SAR 5.10 | Generic · OTC | SPIMACO ADDWAEIH | Withdrawn by MAH · Not Marketed |
| NAZIX NASAL SPRAY 0.05% W-V | 0.05 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 4.75 | Generic · OTC | SPIMACO ADDWAEIH | Withdrawn by MAH · Not Marketed |
| NAZIX NASAL SPRAY 0.1% W-V | 0.1 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 8.25 | Generic · OTC | SPIMACO ADDWAEIH | Withdrawn by MAH · Not Marketed |
| OTRIVIN | 0.1 % | Gel · Nasal use | 1 Tube | SAR 13.35 | NCE · OTC | NOVARTIS | Withdrawn by MAH · Not Marketed |
| OTRIVIN NASAL SPRAY 0.1%(NEBULISER) | 0.1 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 11.40 | NCE · OTC | NOVARTIS | Withdrawn by MAH · Not Marketed |
| XYLO-MEPHA 0.05% NASAL SPRAY | 0.05 % | Nasal spray, solution · Nasal use | 1 Spray Container | SAR 4.80 | Generic · OTC | ACINO PHARMA AG | Withdrawn by MAH · Not Marketed |
Canada Canada — marketed products (Health Canada)
| Brand | DIN | Strength | Form · route | Company |
|---|---|---|---|---|
| DECONGESTANT NASAL SPRAY | 02452812 | 0.1 % / W/V | SPRAY · NASAL | CRLS |
| NASAL DECONGESTANT SPRAY WITH MOISTURIZERS | 02452863 | 0.1 % / W/V | SPRAY · NASAL | CRLS |
| OTRIVIN COMPLETE RELIEF | 02331403 | 0.1 % / W/V | SPRAY · NASAL | HALEON CANADA ULC |
| OTRIVIN CONGESTION RELIEF | 00653330 | 0.1 % / W/V | SPRAY · NASAL | HALEON CANADA ULC |
| OTRIVIN MOISTURIZING CONGESTION RELIEF | 02208903 | 0.1 % / W/V | SPRAY · NASAL | HALEON CANADA ULC |
Prices — United States and England
| Source | Product as listed | Price | Unit / pack | Date |
|---|---|---|---|---|
| NHS Drug Tariff | Xylometazoline 0.05% nasal drops | £2.82 | 10 ml | 1 Oct 2026 |
| NHS Drug Tariff | Xylometazoline 0.1% nasal drops | £2.50 | 10 ml | 1 Oct 2026 |
| NHS Drug Tariff | Xylometazoline 0.1% nasal spray | £2.97 | 10 ml | 1 Oct 2026 |
NADAC: average price US retail pharmacies pay to buy the medicine. NHS Drug Tariff Part VIIIA: basic price reimbursed to pharmacies in England and Wales.
WHO WHO Model List of Essential Medicines (2025)
- 28. Ear, nose and throat medicines [c] · core
Nasal congestion
Local > Nasal > Spray: 0.05% equivalent to 0.5 mg per mL (EMLc) | Local > Nasal > Drops: 0.05% equivalent to 0.5 mg per mL (EMLc)
Safety signals and safety-related labeling changes
- EMA PRAC 31 Oct 2018 PRAC signal: Serious ventricular arrhythmia in patients with long QT syndrome
Action for MAH: update of the product information: Yes - EMA PRAC 14 Jun 2018 PRAC signal: Serious ventricular arrhythmia in patients with long QT syndrome
Action for MAH: update of the product information: No
Combinations containing Xylometazoline
Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.