Is Nitrous oxide + Oxygen authorised in the United Kingdom?

The MHRA category lists of UK marketing authorisations include 4 products containing Nitrous oxide + Oxygen, including DONOPA 50 %/50 % V/V, MEDICINAL GAS, COMPRESSED; ENTONOX MEDICINAL GAS; EQUANOX; NITRONOX INHALATION GAS.

Active substances

Nitrous oxide + Oxygen

Health Canada 3
UK MHRA 4

Open in the medicines table

Canada Canada — marketed products (Health Canada)

Brand	DIN	Strength	Form · route	Company
ALNOX GAS	02071010	50 %; 50 %	GAS · INHALATION	AIR LIQUIDE CANADA INC.
LIQUI-MED ANALGESIC GAS	00693596	50 %; 50 %	GAS · INHALATION	PRAXAIR CANADA INC
MEOPA	02154757	50 %; 50 %	GAS · INHALATION	MESSER CANADA INC.

UK MHRA United Kingdom — marketing authorisations

Product	Authorisation	Holder	Legal status
DONOPA 50 %/50 % V/V, MEDICINAL GAS, COMPRESSED	PL 35326/0009	SOL SPA	POM
ENTONOX MEDICINAL GAS	PL 00735/5017R	BOC LIMITED	P
EQUANOX	PL 15929/0008	AIR LIQUIDE LIMITED	P
NITRONOX INHALATION GAS	PL 17872/0001	MEDICAL GAS SOLUTIONS LIMITED	P

Components

Values as published by each source: SFDA human drug list (4-2026, as published by the Council of Health Insurance; indications from the CHI Daman Drug Formulary), Drugs@FDA, EMA medicines data, Health Canada Drug Product Database (Open Government Licence – Canada), MHRA category lists of UK marketing authorisations (Open Government Licence v3.0), CMS NADAC, NHS Drug Tariff Part VIIIA (NHSBSA Copyright, Open Government Licence v3.0), WHO Model List of Essential Medicines (CC BY 3.0 IGO; regrouped by active substance, not created by WHO), EMA PRAC, US FDA safety-related labeling changes and MHRA Drug Safety Update (Open Government Licence v3.0). Sources and reuse. Not a substitute for the official registers or the product information.